Lec 11 Flashcards

1
Q

Vesicle

A

Phospholipid sphere with cargo proteins

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2
Q

How are vesicles formed

A

Cargo molecules stick to cargo receptors

Clathrin (and other coat protein) bind to flat membranes and bend it into balls, forming vesicles

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3
Q

Coat proteins

A

Surround vesicles

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4
Q

Clathrin

A

When put together they form soccer ball shapes

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5
Q

Adaptin

A

Connects coat proteins/clathrin to cargo receptors

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6
Q

Dynamin

A

Closes the vesicle and separates the vesicle

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7
Q

Removing coat proteins

A

Adaptin is regulated by Ran

It uncoats the protein by when the vesicle is made and Adaptin GTP turns into the inactive Adaptin GDP

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8
Q

Iron transport in humans

A

Red blood cells and hemoglobin

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9
Q

Iron delivery

A

Intestine cell

Blood

Future RBC

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10
Q

Transferrin proteins

A

Made in livir

Transports iron to target

Uses receptor mediated endocytosis

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11
Q

How to vesicles move

Microtubules

A

Microtubules have polarity and a characteristic arrangement in animal cells

Motor proteins when given ATP can walk along microtubules

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12
Q

Kinesin

A

Move from - end to + end along microtubules while holding onto vesicles

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13
Q

Dynein

A

Move from + end to - end along microtubules while holding onto vesicles

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14
Q

Receptor mediated endocytosis uses

A

Dynein

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15
Q

Golgi surrounds the

A

Centrosome

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16
Q

Microtubules come out of

A

Centrosome

17
Q

Moving toward the centrosome is

A

Dynein

18
Q

Moving away from the centrosome is

A

Kinesin

19
Q

How do vesicles fuse with their targe membraines

A

SNAREs

20
Q

v SNARE

A

Vesicle SNARE

in vesicle

21
Q

t SNARE

A

Target SNARE

in plasma membrane

22
Q

Vesicle leaving an organelle are given

A

The appropriate V-snare

23
Q

Vesicles fuse with the target membrane when

A

SNAREs pull together

24
Q

Later the cells are separated and

A

The v-SNARE goes back