Lec 39 Flashcards
1
Q
Cell cycle checkpoints
A
G1
M
G2
2
Q
Cyclin-Cdk complex
A
Kinases phosphorylate target proteins
3
Q
Phosphatases are present in
A
Low numbers but always present
4
Q
Cyclin dependent kinases
Cdks
A
Always at a high level (acting during cell cycle)
5
Q
Cyclins
A
Bind to Cdks and dictate their targets
6
Q
G1 cyclins
A
Prep for DNA replication
7
Q
S cyclins
A
Start DNA replications
8
Q
M cyclins
A
Start prophase (mitosis)C
9
Q
Cyclin makes Cdk
A
Active
10
Q
Cyclin amount
A
Cycles from low to high
11
Q
G1 Cdk means
A
Cdk with cyclin in G1
12
Q
G1 Cdk has
A
2 targets
13
Q
S Cdk has
A
2 targets
14
Q
M cdk has
A
6 targets
15
Q
Cyclin A binds to
A
Cdk2 and moves the T loop which exposes the active site and allows it to bind to targets
