Lec 13 Flashcards
Mitochondrion makes
ATP
Mitochondrion has
Outer and inner layer
Phospholipids
Mitochondrial DNA
Proteins
Mitochondrial DNA
Nucleotides imported from cytosol
ORI in MT
Two replication forks connect two ORIs together
Most proteins in the MT
Made by free ribosomes in the cytosol
Imported by translocase proteins and puts them into proper membrane or space
Translocase in the outer membrane is called
TOMs
Translocase in the inner membrane is called
TIMs
TOM/TIM signal
Protein signaling to import into mitochondria
MT reproduction
ER wraps around MT and pinches it, dividing it
Heme group
Little organic circle found in proteins like hemoglobin that transports oxygen
Heme synthesis
Iron exits lysosomes through DMT1 membrane transport proteins
Iron import + Heme export
Porin proteins in outer membrane move iron in
To get past inner membrane, a specific transporter is used
Iron is used to make hemes
A specific transporter allows the hemes to leave the inner membrane and the porin allows it to leave the out membrane
MT triggers
apoptosis
Cell destruction
Retina specific function of MT
Mutations in mitochondrial DNA can cause blindness