Lec 13 Flashcards

1
Q

Mitochondrion makes

A

ATP

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2
Q

Mitochondrion has

A

Outer and inner layer

Phospholipids

Mitochondrial DNA

Proteins

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3
Q

Mitochondrial DNA

A

Nucleotides imported from cytosol

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4
Q

ORI in MT

A

Two replication forks connect two ORIs together

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5
Q

Most proteins in the MT

A

Made by free ribosomes in the cytosol

Imported by translocase proteins and puts them into proper membrane or space

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6
Q

Translocase in the outer membrane is called

A

TOMs

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7
Q

Translocase in the inner membrane is called

A

TIMs

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8
Q

TOM/TIM signal

A

Protein signaling to import into mitochondria

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9
Q

MT reproduction

A

ER wraps around MT and pinches it, dividing it

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10
Q

Heme group

A

Little organic circle found in proteins like hemoglobin that transports oxygen

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11
Q

Heme synthesis

A

Iron exits lysosomes through DMT1 membrane transport proteins

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12
Q

Iron import + Heme export

A

Porin proteins in outer membrane move iron in

To get past inner membrane, a specific transporter is used

Iron is used to make hemes

A specific transporter allows the hemes to leave the inner membrane and the porin allows it to leave the out membrane

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13
Q

MT triggers

A

apoptosis

Cell destruction

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14
Q

Retina specific function of MT

A

Mutations in mitochondrial DNA can cause blindness

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