Lec 19 Flashcards
Actin filaments structure
Subunit protein- Globular actin (G actin)
Protein filament- Actin filament (F actin)
Actin filaments assemble through
Treadmilling
One F-actin is added to the plus end, resulting in one falling off the minus end
Minus end binding protein
Prevents the loss of actin
Protein Bind plus end
Prevents the insertion of more actin
Middle binding protein
Organize actin into a structure
Cut middle protein
Cuts actin along the midline
F-actin formation is desirable during
Cell crawling and phagocytosis
Nucleating proteins
Anchors minus end and allows plus end to grow
ARP complex
Nucleating protein
F-actin stability example
Intestine cell contains microvilli and cell cortex
Cross-linking proteins
Filamin in the cell cortex that cross-links
Bundling proteins
Villin holds acting together in bundles