Lec 18 Fatty Acid Oxidation Flashcards
extracellular fatty acid carrier
serum albumin
intracellular fatty acid carrier
fatty acid binding protein
double bond in fatty acid is in this configuration
cis
more saturated means blank melting point
high
pufa keeps the membrane blank at low temps… so its like antifreeze
more fluid
sodium hydroxide heating of pure lard creates blank
soap
fatty acid activation requires blank atp
2
glucose activation requires blank atp
1
extracellular pyrophosphate (PPi) is a blank of tooth and bone formation
inhibitor
biphosphonate is used to treat blank by inhibiting extracellular pyrophosphate (PPi)
osteoporosis
Fatty acid activation occurs in the blank via blank and fatty acyl coA becomes fatty acyl carnitine…. only applies to blank fatty acids
cytosol, cat 1, long chain fatty acids C>12
malonyl CoA is most abundant in the blank state and inhibits blank
fed, cat1
carnitine helps burn blank more efficiently
fatty acids
carnitine can be used to treat chronic blank
fatigue
fatty acid oxidation steps are similar to last 3 steps of blank cycle
tca
mcad oxidezes these
medium chain fatty acids (4-12 carbons)
mcad deficiency causes blank
sids, hypoglycemia, decreased fatty acid oxidation
total net yield of 1 palmitate (even chain) is
129 atp
abc system of carboxylase that is required for carboxylation
atp, biotin, carbon
methylmalonic acidosis is due to a deficiency of blank
vitamin b12
stearate C18 net atp production
146
oleate C18:1 net yield
144 (2 atp less because of double bond)
peroxisomal fatty acid beta oxidation is for blank
very long and long chain fatty acids
peroxisomes produce blank but mitochondria dont
hydrogen peroxide
hydrogen peroxide is neutralized via blank
catalase
high ldl and low hdl is blank
dyslipidemia
