FA Synthesis

Question 1

oaa and acetyl coA form blank via blank

Answer 1

citrate, citrate synthase

Question 2

citrate leaves mitochondrial matrix and goes to the cytosol and is broken back down into blank and blank via blank

Answer 2

oaa, acetyl coA, citrate lyase

Question 3

citrate inhibits blank

Answer 3

glycolysis

Question 4

citrate stimulates blank

Answer 4

acc

Question 5

carboxylase requires these (ABC)

Answer 5

acetyl CoA, biotin, citrate?

Question 6

malonyl coA inhibits blank and is an example of blank regulation

Answer 6

cat 1, reciprocal

Question 7

malonyl coA promotes blank by acting as a substrate

Answer 7

fatty acid synthesis

Question 8

allosteric regulation of acc is activation of acc by blank

Answer 8

citrate

Question 9

hormonal control of acc that stimulates acc

Answer 9

insulin

Question 10

insulin stimulates pp1

Answer 10

ok

Question 11

pp1 simtulates acc, glycogen synthase, pyruvate kinase, pfk2

Answer 11

ok

Question 12

pka inhibits acc, pyruvate kinase, glycogen synthase, pfk 2, pp1

Answer 12

ok

Question 13

insulin can inhibit blank

Answer 13

pka

Question 14

ampk is activated via blank

Answer 14

exercise

Question 15

pka is activated by blank

Answer 15

fasting

Question 16

pka and ampk inhibit blank

Answer 16

acc

Question 17

important vitamin for fatty acid synthase

Answer 17

b5

Question 18

fatty acid synthase is arranged in a blank

Answer 18

dimer head to tail conformation with acyl carrier protein in head and cysteine in tail

Question 19

fatty acid synthesis requires blank for reducing power

Answer 19

nadph

Question 20

fatty acid oxidation requires these

Answer 20

nadh, fadh2

Question 21

humans can only add double bond to this position but not these

Answer 21

9….. (12,5)

Question 22

look at last slide for integration

Answer 22

ok

Question 23

glucose, lipids, aa can all make blank and thus blank

Answer 23

pyruvate, acetyl coA