Lec 14 Pyruvate Metabolism Flashcards
pyruvatate that goes through anaerobic metabolism produces blank which cause blank
lactate, cavities
important enzyme for digesting galactose
galactose 1 phosphate (uridylyl transferase)
blank is required for making glycogen, digesting galactose, and making sphingolipid
udp glucose
when galactose can not be metabolized
galactosemia
galactosemia has unmetabolized milk sugars called blank which build up and damage the liver, eyes, kidneys, and brain…..
galactitol
important things used by brain in the fasted state
ketone bodies
center of the entire metabolic scheme
pyruvate
almost anything can be made from blank
pyruvate
enzyme that regenerates nad+ in the human body
lactate dehydrogenase
hangover is due to this molecule in alcohol digestion
acetaldehyde
three subunits of pyruvate dehydrogenase complex
E1, E2, E3
E1 reaction is blank
irreversible
E2 and E3 are both blank
reversible
regulation targets blank reaction because of its irreversibility
E1
what is produced by e2
acetyl coA
what is made by e1 reaction
co2
what is made by e3
nadh
pdc is inhibited by blank which makes ground water toxic
asinine
fast twitch fibers convert pyruvate to blank
lactate
slow twtich fibers convert pyruvate to blank which is converted to blank
acetyl coA, co2 + h2o
cycle that takes glucose from blood and converts it to lactate then the liver uses the lactate and turns it back into pyruvate then glucose
cori cycle
normal amount of blood lactate
1 mM
hyperlactemia is this range of blood lactate concentration
2-5 mM
> 5 mM blood lactate concentration is blank
lactic acidosis
glucose is converted to blank
2 pyruvate
