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ACLAM > JAALASJuly 2016 Random > Flashcards

JAALASJuly 2016 Random Flashcards

1
Q

The elevated plus maze is used to test for anxiety-like behavior or spatial memory?

A

anxiety-like behavior

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2
Q

What behavior does the marble burying test measure

A

neophobia, anxiety and repetitive behavior

records the number of marbles buried in a specific amount of time

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3
Q

How can ES cell contribution to offspring be assessed visually?

A

by coat color

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4
Q

The AVMA guideline on euthanasia recommends that “___” species should not be present when individual animal euthanasia is performed

A

“sensitive” species

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5
Q

A recent study concluded that mice exposed to euthanasia of other animals by CO2 or decaptiation did had no noticeable affect.

A

They did however respond to the noise of the guillotine, whether and animal was being euthanized or not.

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6
Q

Genus and species of Deer mice

A

Peromyscus maniculatus

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7
Q

Are deer mice nocturnal or diurnal?

A

nocturnal

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8
Q

According to this recent study which substrate seems to be ideal for deer mice nest building?

A

brown crinkled paper

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9
Q

What is the mechanism of action of alfaxalone

A

GABA receptor binderWh

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10
Q

Describe myoclonic jerk

A

leg twitching behavior associated with administration of alfaxalone to mice
large amplitude rhythmic movement

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11
Q

genus and species of the goat

A

Capra hircus

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12
Q

T or F.

Compared to sheep goats are considered more sensitive to pain

A

T

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13
Q

What is the mechanism of action of local anesthetics, such as lidocaine?

A

sodium channel inhibition, preventing nerve conduction in pain fiber (A,delta, c)

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14
Q

This recent study concluded that CRI lidocaine improved analgesia with no cardiopulmonary effect in goats

A

T

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15
Q

T or F

Cefovecin has similar pharmacokinetics in dogs and NHPs

A

F

They are vastly different and for that reason cefovecin is no recommended for use in NHPs

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16
Q

T or F

Transdermal fentanyl solution has been approved for use in dogs

A

T

17
Q

Name the reversal agent for Fentanyl

A

Naloxone

a pure opiate antagonist

18
Q

To which receptor sites does Naloxone bind?

A

mu, kappa and delta, highest affinity for mu

19
Q

A recent publications suggest that transdermal fentanyl is not recommended for use in NHPs

A

T

Due to unreliable pharmacokinetics in NHPs (neither the patch nor solution were recommended)

20
Q

What is the most common method of collection of genetic material from mice for genotyping

A

tail biopsy

21
Q

t or f

A recent publication recommends the use of ice-cold ethanol prior to tail biopsy in mice 7-15d of age

A

T

22
Q

What is the acceptable displacement volume of CO2 to use for rodent anesthesia

A

10-30% per minute

23
Q

A recent publication demonstrated a lack of significant effects on physiological, behavioral or histological parameters whether the acceptable flow rate of 10-30% or a much higher chamber displacement rate was used

A

questioning whether the AVMA guideline rate or a much higher rate is more humane

24
Q

What is the likely contributor of ulcerative dermatitis in C57BL6 mice or those on a B6 background?

A

Th-1 driven immune response

25
Q

According to a recent article, what is the recommended treatment for ulcerative dermatitis?

A

nail trimming

26
Q

Genus species, family and order of guinea pig

A

Cavia porcellus, Caviidae, Rodentia

27
Q

T or F

Guinea pigs are born with their eyes open?

A

T

28
Q

What does the term paurangiotic refer to in the Guinea pig eye

A

blood vessels occur only near the optic disc

29
Q

Do guinea pigs have a third eyelid to protect the cornea?

A

no it is vestigial

Also GPs blink only 2-5times every 20 min! They have pronounced tear film stability

30
Q

What are the most common bacterial pathogens associated the conjunctivitis in the GP

A

Chlamoydophila psittaci and caviar

31
Q

T or F

Tritrichomonas muris is a highly transmissible agent that occurs in the GI tract of mice

A

T

typically it is non-pathogenic, but may cause disease in immunocompromised mice

32
Q

T or F

Ronidazole is an antiparasiticide that my be useful in controlling Tritrichomonas muris in mice

A

T

33
Q

What is the primary mechanism of action of isoflurane

A

activation of gamma-aminobutyric acid channels, which increases chloride permeability of neurons

34
Q

genus species of ferret

A

Mustela putorius furo

35
Q

genus species of Sooty mangabeys

A

Cercocebus tays

36
Q

T or F

HCT can affect the accuracy of hand-held glucometers in humans

A

T

37
Q

T or F

Handheld glucometers are less accurate in the state of hypoglycemia

A

T

38
Q

Does arterial or venus blood generally have higher glucose levels

A

Arterial

39
Q

A recent article concludes that human or veterinary hand held glucometers are likely more accurate in NHPs?

A

human

HCT, sampling site, physiologic state might also have an effect on glucose accuracy

ACLAM (32 decks)

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