ImmunoSero Lec (Midterms - Precipitation & Agglutination)

Question 1

developed to detect either antigen or
antibody

Answer 1

Immunoassays

Question 2

involves combining soluble antigen with soluble antibody to produce insoluble complexes that are visible

Answer 2

precipitation

Question 3

process by which particulate antigens such as cells aggregate to form larger complexes when a specific antibody is present

Answer 3

Agglutination

Question 4

considered unlabeled because a marker label is not needed to detect the reaction

Answer 4

precipitation and agglutination

Question 5

initial force of attraction that exists between a single Fab site on an antibody molecule and a single epitope or determinant site on the corresponding antigen

Answer 5

Affinity

Question 6

The strength of attraction depends on the
________________________ of antibody for a particular antigen

Answer 6

specificity

Question 7

Antibodies are capable of reacting with antigens that are structurally similar to the original antigen that induced antibody production

Answer 7

Cross reactivity

Question 8

The more the cross-reacting antigen resembles the original antigen, the ________________ the bond will be between the antigen and the binding site.

Answer 8

stronger

Question 9

Proportionality of the affinity and assay reaction

Answer 9

The higher the affinity, the more sensitive is the assay reaction

Question 10

represents the overall strength of antigen-antibody binding and sum of all the affinities of all the individual antibody-antigen combining sites

Answer 10

Avidity