CC2 LAB: Endocrinology (Quiz 3) Flashcards

1
Q

Study of Hormones

A

ENDOCRINOLOGY

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2
Q

GENERAL FUNCTIONS OF ENDOCRINOLOGY:

A
  1. Regulatory: constancy of chemicals
  2. Morphogenesis: Growth/Development
  3. Integrative
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3
Q

Released because of critical levels of ions/Nutrients

A

Humoral Stimulus

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4
Q

Released caused by neural input

A

Neural Stimulus

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5
Q

Released caused by another hormone

A

Hormonal Stimulus

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6
Q

Release hormones to blood (by diffusion)

A

Endocrine glands

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7
Q

Could be Strictly endocrine or organs that have hormone production as one of its function

A

Endocrine glands

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8
Q

From the Greek word “Hormon” meaning

A

“to set in motion”

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9
Q

Secreted by cells to extracellular fluid

A

Hormones

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10
Q

Long distance chemical signals

A

Hormones

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11
Q

Hormones regulate metabolic functions which provide changes in:

A
  1. membrane permeability 2. stimulate protein
  2. synthesis regulatory molecules
  3. activate or deactivate enzyme
  4. induce secretory activity 6. stimulate mitosis
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12
Q

Action Categories: synthesize in one location

A

Endocrine

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13
Q

Action Categories: synthesized in the endocrine cells

A

Paracrine, Autocrine & Juxtacrine

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14
Q

Action Categories: released to lumen of gut, binds to cells of gut

A

Exocrine

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15
Q

Action Categories: synthesized in neurons

A

Neurocrine

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16
Q

Action Categories: synthesized in nerve endings

A

Neuroendocrine & Neurotransmission

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17
Q

Action Categories:
Enters circulation and binds specific cells at distant site to elicit response

A

Endocrine

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18
Q

Action Categories: Enters interstitial spaces and binds specific receptor in adjacent gland for its effect

19
Q

Action Categories: Enters interstitial space and binds specific receptor cell of the origin to autoregulate its function

20
Q

Action Categories: Remains associated with plasma membrane and acts on adjacent receptor by direct cell to cell

A

Juxtacrine

21
Q

Action Categories: moves to extracellular space, binds to receptors in nearby cells for its action

A

Neurocrine

22
Q

Action Categories: enters the circulation, interacts with receptor of cells of distant sites

A

Neuroendocrine

23
Q

Action Categories: crosses synapse and binds to receptors in another neuron affecting its action

A

Neurotransmission

24
Q

cyclal patterns of hormone release

A

Biorhythms

25
Biorhythms types
1. Circadian/Diurnal 2. Infradian – occur over a period of time greater than 24hours 3. Ultradian – less than 1 day
26
Hormone concentration is controlled by:
1. Rate of production/Synthesis 2. Efficiency of delivery 3. Metabolism
27
Chemical Categories: Hydrophobic (non-water soluble)
Steroids
28
Chemical Categories: Water soluble
Polypeptides
29
Chemical Categories: Freely circulating
Amino Acid derived
30
Example of Steroids
Cortisol Progesterone Estrogen Testosterone Aldosterone
31
Example of Polypeptides
PTH Insulin LH FSH TSH TRH ACTH Prolactin GH Calcitonin
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Example of Amino Acid Derived
Epinephrine Norepinephrine T3 T4
33
Chemical Categories: Bound to proteins
Amino Acid derived
34
Chemical Categories: Circulate freely & Only when needed
Polypeptides
35
Mechanism of Hormone Action
1. Cell Surface Receptors 2. Nuclear Receptors
36
Interaction of hormones to target cells:
1. Permissiveness 2. Synergism 3. Antagonism
37
hydrophobic, from cholesterol and needs a carrier protein
Steroids
38
hydrophilic, no need of carrier and usually in low concentrations
Proteins
39
when 1 hormone cannot exert its full effect without another hormone being present
Permissiveness
40
more than one hormone produce same effects on target cells
Synergism
41
one hormone opposes the action of another hormone
Antagonism
42
Target Cell Specificity response depends on
1. Blood levels of hormones 2. number of receptors 3. Affinity of receptors to hormones
43