Immunology Flashcards
What are the sx of Chediak Higashi syndrome?
recurrent bacterial infections, partial oculocutaneous albinism, photophobia, nystagmus, and peripheral neuropathy.
Defect in LYST
Primary Biliary Cirhosis is associated with which antibody?
anti-mitochondrial
(mit-turn-yellow)
What is the defective mechanism in Chediak Higashi Syndrome?
abnormal lysosomal trafficking protein that results in defective phagolysosome formation
describe Job’s syndrome (hyperIgE)
eczema, eosinophilia, and recurrent skin and pulmonary infections
What type of hypersensitivity reaction in Grave’s Disaese?
Type II, noncytotoxic
In what disease will you see deposition of DNA and anti-DNA antibodies?
SLE (type III)
Leukocyte adhesion deficiency type one is due to a def. in what CD?
dec in CD18
Be ware of mixed connective tissue disorder. How does it present?
What is the antibody?
All kinds of symptoms similar to Lupus, CREST, or Sjogren’s
Anti-ribonucleoprotein
what are the cell markers on Hodgkin Lymphoma?
CD 15 and 30
What two types of infections are seen in DiGeorge’s Syndrome?
Viral and fungal
Which disease featuring cavitary lesions in the lungs is a delayed hypersensitiviy reaction?
Tuberculosis!
What is the FEV1/FVC ratio in asthma?
DEcreased
Which disease has a negative nitralizine blue test (with recurrent infections)
Chronic Granulomatous Disease
What type of HSN rxn is post-streptococcal glomerulonephritis?
HSN type III
What are the assox sx of dermatitis herpetiformis?
What is the Ig deposition?
Abdominal pain, diarrhea, steatorrhea
IgA
