HoW aRe We FeEliNg ToDAy?? Yeah, I aM nOt FeELing GOod HaAhAhA

Question 1

STATS

Answer 1

Question 2

if a population is decreasing in size, how does the prevelence of a dz change?

Answer 2

it increases because the population is decreasing

Question 3

stats

Answer 3

Question 4

What are the layers of a crycothyrotomy?

Answer 4

skin

superficial cervical fascia

deep fascia

cricothyroid membrane

Question 5

INH inhibits what enzyme path?

Answer 5

ALA synthase by inhibiting pyridoxine phosphokinase

Question 6

amphotercin B is most notable at causing what side effect?

what should be monitoed?

Answer 6

nepthrotoxicity

mointor serum K and Mg levels as hypokalemia and hypomagnesiumia is common and can cause RTA

Question 7

what will be the result of treating normocytic anemia caused by CKD with EPO?

Answer 7

increased progenitor cell differentiation obviosuly

Question 8

syphiliis diagnosis

Answer 8

Question 9

ab to neissieria are lilely directed at what?

Answer 9

at the pili to help avoid attachment to oropharynx

antigenic variation makes it hard to build up immunity to these pili tho

Question 10

what are the characteristics of anaplastic cells?

Answer 10

loss of polarity, coalesce into sheets and islands

variation in shapes and sizes

large nuclei, coarse chromatin

numerous abnomral mitotic figures

giant, multinucleated tumor cells

ex: brain tumor with giant cells

Question 11

what kind of gene modification is responsible for the manifestation of huntington’s dz?

Answer 11

histone deacetylation

Question 12

why is the h flu vaccine conjugated with tetanus toxoid?

Answer 12

to help induce a T cell mediated response to prolong immunity thru B cell production

Question 13

name a stimulant laxattive that stimnulates the enteric plexus to increase GI motility

Answer 13

bisacodyl

Question 14

catheter wave forms

Answer 14

Question 15

if someone has carotid body sensitivity, what nerve may be involved?

Answer 15

glossopharyngeal

Question 16

male pt with large anterior mediastinal mass and elevated bHCG and AFP probably has what?

Answer 16

(nonseminomatous) GCT or malignant teratoma

Question 17

VPN or thayer martin agar is considered ____

Answer 17

selective

Question 18

effusions

Answer 18

Question 19

knee mri posterior coronal plane

Answer 19

Question 20

homogenous, pale eosiniphilic/pink cytoplasm in hepatocytes or ground glass hepatocytes means

Answer 20

hep B

Question 21

which is more likely to cause satiety and weight loss for db drugs?

Answer 21

GLP1 agonists

DDP4 inhibitors are less likely to cause weight loss

Question 22

GABA agonists in cerbreal palsy?

Answer 22

reduce spacitiy by increasing GABA activity (which is inhibotoru)

Question 23

is eelvated CK directly related to mitochondrial damagE/

Answer 23

no just related to cell membrane damage boooo

Question 24

amphotercin and NYSTATIN bind to what?

Answer 24

ergosterol and poke holes

azoles inhibit synthesis of ergosterol

Question 25

elevated Ca levels in sarcoidosis are related to what?

Answer 25

activated macropahges note there can be elevated ACE and hypercalciruia

Question 26

got it right but review

Answer 26

Question 27

what is the treatment for mycoplasma oneumoinia ?

Answer 27

protein synthesis inhibitor | (macrolides tetracyclines)

Question 28

itchiness after morpine, abx, contrast?

Answer 28

IgE independent mast cell degranulation

Question 29

what will you find in the stool of storngiolodies?

Answer 29

rhabiditiform larvae

Question 30

aging lung

Answer 30

Question 31

positive birefringement particlaes with dense worled nodules

Answer 31

silica

Question 32

propofol is a lipophilic drug meaning

Answer 32

it gets redistributed into the tissues

Question 33

draw

Answer 33

Question 34

LDL R increase or decrease with statins?

Answer 34

increase in density

Question 35

what is a an easy measurement for VHL patients?

Answer 35

plasma metanephrnes include: RCC, pheochromocytomas, brain/retina hemangioblasromas

Question 36

amyloid is seen in what aged brain dz?

Answer 36

alzehimers

Question 37

metoprolol (cardioselective) is better than propranolol in what case?

Answer 37

AMI

Question 38

chronic lymphadema (even if its not assox with radaition) causes rosk for what?

Answer 38

angiosarcoma

Question 39

PV is due to

Answer 39

JAK2 mutation which makes cells more sensitive to growth signals

Question 40

AZA vs mycophenolate

Answer 40

Question 41

staph aureus has what virulence factor

Answer 41

protein A (not IgA) functions to bind the Fc portion of IgG leading to impaired complement activation, opsonization and phagocytosis

Question 42

in a gallstone ileus, where is the blcok?

Answer 42

in the ileum

Question 43

baby with low total T4, normal free T4 and TSH has what? thyroid dysgenieiss is

Answer 43

TBG deficeincy most common cause of hypothyroid in infancy but is normally asyx at first and TSH would be high and T4 would be low

Question 44

fidoximccin (related to macrolides) has what MOA?

Answer 44

binds and inhibits the sigma subunit of RNA polymerase can tx C diff

Question 45

stenotic vs normal kidney

Answer 45

Question 46

what arteries are assox with which parts of duodenum

Answer 46

Question 47

ERythrocytes can do this and make no ATP as a result

Answer 47

Question 48

WHAT SI THE FUNCTION OF BETA LACTAMASE INHIBITORS LIKE -BACTAMS, AND CLAVILUNIC ACID?

Answer 48

PREVENT BETA LACTAMSE FROM INACTIVATING THE DRUG

Question 49

PSEUDOMONAS AND DIPHTERIA HAVE WHAT IN COMMON?

Answer 49

EXOTOXIN THAT RIBOSYLATES AND INACTIVATES FACTOR ELONGATION FACTOR 2

Question 50

ACUTE HEPATITS FROM MOST HEP VIRUS CAUSE WHAT IN LIVER CELLS?

Answer 50

HEPATOCYTE BALLOONING/SWELLING AND APOPTOSIS

Question 51

BURR CELLS AND HELMET CELLS ARE ASSOX WITH WHAT?

Answer 51

TRAUMATIC HEMOLYSIS FROM MICROANGIOPATHIC HEMOLYTIC ANEMIA OR MECHANICAL RED CELL DESSTRCTION CAN ALSO BE FROM PROSTEHETIC VALVES

Question 52

ALONG WITH HISTMAINE, WAHT ELSE CAN BE RELEASED DURING ANAPHYLAXIS?

Answer 52

TRYPTASE

Question 53

HIGH AFFINITY RECEPTOR AGGREGATION AND DEGRANULATION LEADS TO WHAT?

Answer 53

MAST CELL DEGRANULATION AND ANAPHYLAXIS

Question 54

KNOWW

Answer 54

Question 55

NEPHROTIC SYNDROME IN RA CAN BE ASSOXIATED WITH WHAT?

Answer 55

AA AMYLOID DEPOSITION

Question 56

DISTAL SYMETIRC POLYNEUROPATHY CAN BE TREATED WITH WHAT?

Answer 56

AMYTRIPTYLINE

Question 57

NSAID INDUCED KINDYEN DAMAGE CAN BE FROM WHAT?

Answer 57

IMPAIRED AFFERENT ARTERIOLAR VASODILATION