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Stuff I Get Wrong > Getting Dirty with Dirty Medicine > Flashcards

Getting Dirty with Dirty Medicine Flashcards

1
Q

which HLA with MS?

A

HLA DR2

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2
Q

HLa DR3 is assox with what?

A

SLE

goodpastures

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3
Q

HLA DR4

A

RA and DM1

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4
Q

HLA DR7 is assox with what?

A

nephrotic syndrome

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5
Q

HLA b8 assox wit what?

A

MG and Graves

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6
Q

Ulcerative colitis is assox with what findings?

A

inflammation of the intra and extrahepatic bile ducts

primary sclerosing cholangitis

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7
Q

which conditions are assox with BOTH UC and Chrons ?

A

ankylosing spondylitis

sacroillitis

uveitis

erythema nodosum

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8
Q

extrophitic papillary carcinoma of the bladder is assox with which carcingoen?

A

naphtalymine (aniline dye)

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9
Q

nitrosamines (smoked meat) are assox with which cancer?

arsenic (metalloid in cig smoke) assox with which cancers?

vinyl chloride (PVC) assox with which cancer?

aflatoxin (aspergillus toxin) assox ith which cacner?

A

stomach cancer

SCC and angiosarcoma of the lvier

angiocarcinoma of the liver

hepatocelluar carcnoma

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10
Q

unilateral renal agenesis

A

developmental failure of the ureteric bud and metanephric mesenchyme

RET defect, AD

APLASIA

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11
Q

IN GENERAL, across all age groups, what is the most common cause of mengiitis

A

strep oneumo

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12
Q

hy dirty med

A
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13
Q

what type of casts do you see in the urine of someone abusing cocaine?

A

RBC casts due to hypertensice urgency/emergency

HTN in the stem is like 190sustolic

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14
Q

hy casts

A
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15
Q

testicular pain HY

A
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16
Q

kidney stone shapes

A
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17
Q

stones and assoxiations

A
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18
Q

HY associations

A
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19
Q

which immunosuppresent can cause gingival hyperplasia?

A

cyclosporine

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20
Q

drug MOAS

A
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21
Q

AE of immunospurepsents

A
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22
Q

seziure meds AE

A
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23
Q

where is the tail of the pancras?

A

splenorenal ligament

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24
Q

parvo uses what receptor?

A

red blood cell p antigen

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25
Q

contraction alkalosis

A

loss in fluids

RAAS activated

PCT-bicarb reabsorp, Na retention, H loss

CD-K excrecretion

pH increases

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26
Q

straw or slightly blood nipple discharge

A

intraducrtal papilloma

benign polypoide epithelial tumor in the lactiferous ducts

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27
Q

HY pagets of breat

A
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28
Q

phyllodes HY

A
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29
Q

DCIS HY

A
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30
Q

fobroadenoma hy

A
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31
Q

DELIRUM IN OLD PEOPLE FROM UTIS DUE TO WHAT NTM?

A

ACH

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32
Q

hy pscyh

A
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33
Q

NF1 mutation causing lisch nodules looks like wahT?

A
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34
Q

papilledema

A
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35
Q

keiser flescher rings

A

wilsoms

36
Q

other hy eye

A
37
Q

48hrs after mi a risk for

A

fibrinous pericarditis

38
Q

hy mi

A
39
Q

histology/phatophys post-mi

A
40
Q

more hy post mi

A
41
Q

aminoglycosides and se

A

nephrotox

42
Q

drug moas

A
43
Q

Se for TMP SMX

A
44
Q

AE of tetra

A
45
Q

chloramphenocol hy se

A
46
Q

se of macrolides

A
47
Q

hy drug 1

A
48
Q

hy drug 2

A
49
Q

in anti phospholipid antibody syndrome, what is the autoantibodies targeting?

A

autoantibodies against platelet membranes

50
Q

antiphosphplopid ab syndrome (SLE with cardiolipin ab)

A
51
Q

b9 vs b12 def

A
52
Q

hy pathwyas

A
53
Q

describe pagets disease of bone?

A

imbalance between osteoblast and osteoclast

bone pain, hats fit tighter

elevated ALKP

assox with high output cardiac failrue

54
Q

osteomalacia

A
55
Q

osteopetrosis

A

kids

thick fracture prone bone

56
Q

erythema nodusom can come from what fungus?

A

coccidiomycosis

57
Q

obsucre causes of coccidiomycoses

A
58
Q

therapeutic index

A

these drugs are widly lethal

theophyline digoxin warfarin lithium

59
Q

drug ae hy

A
60
Q

amyloid in the thyroid means what mutation?

A

Men 2a/2b

medullary carcinoma of the thyroid

61
Q

thyroid cancer mutations

A
62
Q

key words for diff thyroid cancers

A
63
Q

cell connections

A
64
Q

hypothalamus

A
65
Q

more hypothalammus

A
66
Q

sturge webber

A

sporadic inheritance

soomatic mutation in GNAQ (which should stabilize capillary web)

port wine stain on face, leptimemnigral angioma, episclera hemangiooma

seizures, IDD, early glaucoma

(WEBber-capillary web issue)

67
Q

tuberous sclerosis

A

AD

gene in TSC1 cr 9 and TSC2 cr 16 (tumor supr genes)

make hamertin and tuberin

ash leaf spots, shagreen patch, cardiac rhadomyoma, renal angiomylolipoma, ungal fibroma, adenoma sebaceoum

ONLY ONE with rhabdoMyoma and angioMYOlipoma

lots of Muscle for TUBAs

68
Q

VHL disease

A

AD

deletion of VHL on cr 3 (tumor spr gene)

overgrowth of protien

bilateral RCC, pheochromocytoma

hemangioblastoma and angioomas

von HARP lindo

H-hemangioblastoma

A-angioma

R-RCC

P-pheochromocutomas

69
Q

NF-1

A

AD

gene NF-1 altered on cr 17 (tumor surp gene to inhibit ras)

cafe au lait spots, neurofibromas, optic gliomas, lisch nodules (pigmented irs/hemartomas)

axillary hyperpigmentation, pheochromocytomas, wilms tumor, scoilois, bone involvment

70
Q

NF-2

A

AD

NF2 gene (chr 22, tumor spr gene)

merlin (scwhannin)

bilateral acoustic shwanomma with tinnitus, sensoneural loss, facial apresis, facial parasthesias

cerebellopontine angle

epindymoma, meningioma, juvenile cataracts

71
Q

hep B serology

A

acute infection: HBsAg and HBeAg

infected hepatocytes: hbcag and makes anti-hbc (igm and igg)

HBeAg goes away and HbeAb is made

last ab is Anti-HBs goes up, HBsAg leaves

72
Q

HBsAg

HbEAg

HbcAg

Anti-HBc

Anti-HbE

Anti-HbS

A

acute or chronic-S for sick

E-easily spread, replication/transmission

core ag is useless, can’t be detected

previous or current infection, IgM-acute, IgG-chronic

c-come across HpB

low transmission, anti-E-anti-easily spread

immune/recovery/vax-anti-Sick

73
Q

awake alert

awake tired

A

beta waves-busthing out work

alpha waves-about to fall asleep

74
Q

NonREM

N1

N2

N3

REM

A

theta waves

K complexes and sleep spindles

delta waves

beta waves (like being awake)

75
Q

N1

A

theta

lightest stage of sleep

MYOCLON1C jerks

5/10% of total sleep

76
Q

N2

A

k complex, sleep spindles

bruxism

50% of sleep

77
Q

N3

A

delta waves

deepest sleep

GH released

10-20% of sleep, decreases throughout the night

78
Q

REM

A

beta

atonic, immobile, autonimic increases (penile tumescence) boners with beta waves

each phase 90-120min, 15%

79
Q

n1 pathology

N2 pathology

N3

REM

A

OSA increases in N1

bruxissm

sleep walking, night terrors, bedwetting, confused if woken

MDD-decreases REm latency (go into REM faster), increased density and duration of REM

80
Q

HMO

A

limited panel of physicians, required referrals from PCP, in network coverage

81
Q

PPOs

A

out of network, not covered as well, more expensive, no referrals

82
Q

EPO

A

same as HMO but smaller

83
Q

POS

A

out of netowrk allowed but in network to reduce cost, recwuires referall, basically like a HMO and PPO mixed

84
Q

capitation

A

docs receive a set amount per patient per time regardless of how much pt utilizies serrvices

used by HMOs

risk pool

each cap is a set dollar amount

85
Q

bundled payments

A

set amount per service divided by all providers based on health outcomes

incentivised to improve patient outcome

organization must pay for unexpected use or complications

86
Q

fee for service

A

pt pays for each service

volume over clinical outocme

discounted fee for service-pt pays predetermined rate (PPO)

Stuff I Get Wrong (34 decks)

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