IC wk 2 Flashcards

1
Q

cephale fase

A

n. vagus > acetylcholine > parietale cel, antrale cel (gastrine) en ECL cel (histamine)
- histamine belangrijkst

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2
Q

gastric fase

A

G-cel stimulatie > gastrine > histamine

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3
Q

intestinale fase

A

H+, duodenum > D-cel, somatostatine

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4
Q

pernicieuze anemie

A

auto-immuunreactie tegen pariëtale cellen, deze worden inactief > zuurproductie valt volledig weg en veel gastrine ter compensatie, maar werkt niet

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5
Q

Zollinger Ellison syndroom

A

gastrine producerende tumor in pancreas > zuurproductie omhoog

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6
Q

ulcus duodeni

A

zuursecretie is basaal verhoogd en zuurproductie is nog normaal stimuleerbaar

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7
Q

ulcus ventriculi

A

zuurproductie neemt af, gastrine normaal-licht verhoogd

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8
Q

diagnostiek

A

endoscopie, CT/MRI/BOZ, biomarkers, bloed, ademtesten, pathologisch onderzoek, ERCP, functionele testen (manometrie, pH)

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9
Q

dysfagie

A

klachten met voedselpassage, kan in keel of achter borstbeen

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10
Q

oorzaken dysfagie

A

achalasie (motorisch), ziekte mond/tong, neuromusculair, motoriek verstoring, extrinsieke druk, intrinsieke oorzaak

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11
Q

Schatzki ring

A

vernauwing distaal in slokdarm, ring van mucosa

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12
Q

slokdarm spasme

A

dysfagie bij vast en vloeibaar, intermitterend

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13
Q

dysfagie, vloeibaar en vast, reflux, gewicht stabiel

A

achalasie: verwijde slokdarm, LES relaxeert niet

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14
Q

achalasie behandelen

A

Heller chirurgie, sluitspier oprekken (POEM, ballon, botox)

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15
Q

muceuze cellen

A
  1. mucine secretie
  2. luminale HCO3- secretie
  3. Herstel bij beschadiging
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