Hyposecretion & Hypersecretion

Question 1

hypersecretion

Answer 1

too much of a hormone

Question 2

hyposecretion

Answer 2

too little of a hormone

Question 3

hyposecretion etiology

Answer 3

a) hormones require chemical components ingested or manufactured for synthesis. if these components are lacking then the hormone may be synthesized, but with a de Fx
b) necessary resources are there for synthesis and Fx, but there is a genetic metabolic defect (ex. missing Es)
c) some hormones stores after synthesis and other used right away. trophic hormones stimulate the growth of tissue, if these hormones are not stimulated to be released and used then atrophy of tissue occurs and a l/o Fx
d) adequate quantity, resources and stimulation BUT the receptor is defective
e) suppressive therapy –> if hypersecretion corrected by Sx or with drugs, hyposecretion could result
f) autoimmunity
g) non-secretory tumors develop in an endocrine gland, which destroy normal cells and inc malignant cells that do not contribute to the Fx of normal cells

Question 4

hypersecretion etiology

Answer 4

a) excessive trophic stimulation –> produce too much hormone –> bind to receptors to produce an action repeatedly
b) defective negative feed back loop –> production of hormone no longer ceases once it is not needed –> continuous production of hormones
c) secretory tumor –> tumor initially will mimic function of tissue of origin –> as malignant cells divide, then more cells are present to produce hormone –> inc hormone production