Cushing's Syndrome (Adrenal Gland)

Question 1

etiology/pathology of adrenocortical hypersecretion

Answer 1

• ant. pituitary tumor or hyperplasia –> ACTH hypersecretion
• cortical tumor or hyperplasia = excessive cortisol production and dec ACTH
• pituitary tumor or hyperplasia = excessive ACTH production, resulting in excessive cortisol production
• ectopic tumors

Question 2

Cushing’s syndrome

Answer 2

• excess cortisol production (glucocorticoid hypersecretion)