Fever + CRP (Inflammation) Flashcards
1
Q
pathogenesis of fever
A
1) body’s IR triggered by exogenous pyrogens which trigger endogenous pyrogens that bind to PGE2
2) PGE2 sends signal to hypothalamus which then increases temp set points via cAMP
2
Q
C-reactive protein (CRP)
A
- protein synthesized (secreted by liver during inflm
- impt serum marker for inflm
3
Q
serum marker
A
components in blood that can determine where disease is taking place/the extent of disease damage
4
Q
Fx of CRP
A
aids complement in defense
5
Q
non-specific marker
A
indicates inflm is occurring but not WHERE inflm is occurring (ex. CRP)
6
Q
what other marker is CRP for
A
atherosclerosis (inc lvls of CRP)
