heart failure and cardiomyopathies - Sheet1 Flashcards

1
Q

What is heart failure?

A

A condition in which the heart is unable to pump blood efficiently to meet the body’s metabolic demands due to structural or functional disorders.

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2
Q

What is HFpEF?

A

Heart failure with preserved ejection fraction (EF ≥ 50%). The heart’s pumping ability is preserved, but the heart cannot fill properly.

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3
Q

What is HFrEF?

A

Heart failure with reduced ejection fraction (EF < 40%), where the heart has difficulty pumping blood out.

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4
Q

What are common causes of heart failure?

A

CAD, myocardial infarction, hypertension, valvular disease, myocardial toxins (chemotherapy, cocaine), untreated tachycardia, alcohol abuse, idiopathic causes.

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5
Q

What is the difference between left-sided and right-sided heart failure?

A

Left-sided heart failure primarily affects respiratory function (pulmonary congestion), while right-sided heart failure affects peripheral circulation (e.g., edema, ascites).

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6
Q

What are the manifestations of left-sided heart failure?

A

Respiratory symptoms: Paroxysmal nocturnal dyspnea, cough, crackles, wheezes, tachypnea, restlessness, confusion, orthopnea, exertional dyspnea, fatigue, cyanosis.

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7
Q

What are the manifestations of right-sided heart failure?

A

Peripheral symptoms: Fatigue, increased peripheral venous pressure, ascites, enlarged liver and spleen, distended jugular veins, anorexia, GI distress, weight gain, dependent edema.

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8
Q

What is high-output heart failure?

A

A condition where the heart cannot meet metabolic needs despite normal or elevated cardiac output due to factors like anemia, septicemia, hyperthyroidism, or beriberi.

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9
Q

Common causes of high-output heart failure?

A

Anemia (low O2 carrying capacity), septicemia (vasodilation lowers SVR), hyperthyroidism (increased metabolic demand), and beriberi (thiamine deficiency, impaired heart function).

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10
Q

What is dilated cardiomyopathy?

A

Dilated cardiomyopathy is a condition where the ventricles of the heart dilate, leading to impaired systolic function, decreased ejection fraction, and congestive heart failure.

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11
Q

What are the common causes of dilated cardiomyopathy?

A

Common causes include idiopathic (most common), ischemic heart disease, drug toxicity, hyperthyroidism, valvular heart disease, and heavy alcohol use.

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12
Q

What are the manifestations of dilated cardiomyopathy?

A

Manifestations include dyspnea from pulmonary congestion, palpitations, dizziness, hypertension, and heart murmurs.

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13
Q

How is dilated cardiomyopathy diagnosed?

A

Diagnosis is made through history and physical exam (H&P), echocardiogram, and MRI.

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14
Q

What is hypertrophic cardiomyopathy?

A

Hypertrophic cardiomyopathy is characterized by thickening of the myocardium, often due to hypertension or valvular stenosis, or inherited disorders, leading to heart failure.

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15
Q

What are the common causes of hypertrophic cardiomyopathy?

A

Common causes include idiopathic origins, hypertension, and valvular stenosis.

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16
Q

What are the manifestations of hypertrophic cardiomyopathy?

A

Manifestations include dyspnea, angina, fatigue, dizziness, and palpitations.

17
Q

How is hypertrophic cardiomyopathy diagnosed?

A

Diagnosis is made through history and physical exam (H&P) and echocardiogram.

18
Q

What is restrictive cardiomyopathy?

A

Restrictive cardiomyopathy involves rigid and noncompliant ventricles, which impede ventricular filling, raise filling pressures, and lead to congestive heart failure, often affecting the right side.

19
Q

What are the common causes of restrictive cardiomyopathy?

A

Common causes include infiltrative diseases like amyloidosis or hemochromatosis.

20
Q

What are the manifestations of restrictive cardiomyopathy?

A

Manifestations include jugular vein distention (JVD), hepatomegaly, lower extremity edema, and dysrhythmias.

21
Q

How is restrictive cardiomyopathy diagnosed?

A

Diagnosis is made through history and physical exam (H&P) and echocardiogram.