HD EOYS6 Flashcards
Which virus has differing chronicty depending on age at infection?
EBV
Hep B
VZV
Hep C
HSV
Which virus has differing chronicty depending on age at infection?
EBV
Hep B
Hep C
HSV
Name a virus that is usually asymptomatic in early life but is typically worse in 15-25 years old
EBV
Hep B
VZV
Hep C
HSV
Name a virus that is usually asymptomatic in early life but is typically worse in 15-25 years old
EBV
Hep B
VZV
Hep C
HSV
Which of these is not in the top three reasons for sepsis and meningitis?
Neisseria meningitidis
Streptococcus pneumoniae
Haemophilus influenzae B (HiB)
Respiratory syncytial virus
Which of these is not in the top three reasons for sepsis and meningitis?
Neisseria meningitidis
Streptococcus pneumoniae
Haemophilus influenzae B (HiB)
Respiratory syncytial virus
Which of the following causes scarlet fever?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Which of the following causes scarlet fever?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Which of the following is group A strep?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Which of the following is group A strep?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Which of the following is group B strep?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Which of the following is group B strep?
Streptococcus bovis
Streptococcus agalactiae
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus viridans
Artesunate is the treatment for
EBV
VZV
Malaria
T. gondii
CMV
Artesunate is the treatment for
EBV
VZV
Malaria
T. gondii
CMV
IV ganciclovir is the treatment for? [1]
CMV
Describe pathophysiology caused by Corynebacterium diphtheriae
- What process does the A-B subunit inhbit? [1]
- What are the pathological consequences for the heart [2] & nerves? [3]
- What structural change occurs in mouth? [1]
Diphtheria toxin: A and B subunits inhibits protein synthesis:
Heart implications:
- Myocarditis
- Heart block
Nerve implications:
- Difficulty swallowing
- Paralysis
- Diplopia
Get pseudomembrane in mouth
What are the four bacilli gram +ve organsims need to know? [3]
Corynebacterium
Listeria
Bacillus: cereus (food pois); anthracis (anthrax)
Clostridium: tetani botulinum, difficile
Describe the pathogenesis of meningococcal disease
Which two molecules are activated by LPS that cause inflammatory cascade for meningococcal disease? [2]
IL-6
TNF-α
Name three most common causes of septicaemia and meningitis [3]
Streptococcus pneumoniae
Neisseria meningitidis
* Group B and C
* Increase in Group W since 2009
* Teenagers, university students
Haemophilus influenzae B (HiB)
Which of the following causes “Pneumococcus”
Staphylococcus
Streptococcus
Enterococcus
Staphylococcus
Streptococcus
Enterococcus
Explain three immune defects that could predispose an individual to an pneuomococcal infection [3]
- HIV infection
- Hypogammaglobulinaemia (low levels of IgG due to B cells not being able to mature)
- Absent / non-functional spleen
Give three reasons for an absent / non-functional spleen [3]
Congenital asplenia
Traumatic removal
Hyposplenism (eg sickle cell)
Name 4 invasive features of Streptococcus pneumoniae infection
- Meningitis
- Sepsis
- Osteomyelitis
- Septic arthritis
- Peritonitis
- Lobar pneumonia
- Empyema
Name the two most common presentations of Pneumococcal pneumonia (Streptococcus pneumoniae) [2]
- Lobar pneuomonia
- Empyema (a serious complication characterized by pus and bacteria in the pleural)
How would you manage empyema caused by pneuomococcal pneuomonia? [2]
Chest drain
Video-assisted thoracoscopic surgery (VATS)