Genetics Module 2.2 Flashcards
are genes located on the same chromosome
Linked genes
are often inherited together into the same gametes
linked genes
these are closely associated linked genes that are always inherited together
complete linkage
these are associated linked genes that partially segregate from each other during gamete formation
incomplete linkage
types of linkage notation
- Cisform or coupling phase
- Transform or repulsion phase
linkage notation
All dominant alleles (AB) or recessive alleles (ab) are on the same chromatid.
Cis form or coupling phase
linkage notation
Both the dominant allele and recessive allele of linked gene A and B are on the same chromatid.
Trans form or replusion phase
it is the process of determining if two genes are linked, or if they tend to be inherited together
linkage determination
types of linkage determination
- deviation
- non-comfornity
linkage determination
1:1 (monohybrid) and 1:1:1:1 (dihybrid) test cross ratio
deviation
linkage determination
9:3:3:1 F2 phenotypic ratio
non-comfority
linkage determination
formula for linkage value
linkage value= (total number of crossover types/total number of population) x 100
refers to the inhibition of further cross over events by crossover event in a nearby region of the chromosome
interference
is the ratio of the observed number of double crossovers to the expected number of double crossovers
coefficient coincidence
formula for coefficient coincidence (cc)
cc= actual DCO/expected DCO