Exam - Placentation and Ggestation Flashcards
what does the inner cell mass become
fetus
what happens to the chorion after hatching
it rapidly grows l laterally to occupy space within the uterus
what must the conceptus do
move to a proper location in the uterus
stimualte production of histotroph by endometrium
prevent luteolysis
inhibit maternal immune system
establish a placenta
where is the proper placentation location in the cow
close tot he bifurcation of the ipsilateral uterine horn
what does the prevention of luteolysis require
P4 dominated uterus - maintain it non-contractile
what percentage of embryonic genome is foreign
50%
why must a placenta be established
more definitive attachment
more effective transfer nutrients/wastes between mother and fetus
what is the strategy in rodents for retaining. luteal function during early gestation
luteotrophin release by mating (LH/prolactin)
what can infertile mating in rodents lead to
pseudopregnancy
strategy for retaining luteal function during early gestation in primates
chorionic gonadotrophin - similar to LH, supports CL
strategies for retaining luteal function during early gestation in cows, sheep, sows, mares
antiluteolytic mechanism - prevents luteolysis
what do all strategies for retaining luteal function during early gestation result in
maternal recognition of pregnancy
which cells are most important in the luteolytic process
uterine epithelial cells in the uterine horn ipsilateral to the corpus luteum bearing ovary
what does oxytocin do in the luteolytic process
it binds to the oxytocin receptor - the uterus which stimulates PGF2a
once stimulated, what does PGF2a do in luteolytic process
it increases in uterine vein and then is counter currently transferred to ovarian artery which initiates luteolysis
