Exam 6 - Meds and the Elderly Flashcards
Lasix, NSAIDs, Dilantin…
Highly protein-bound drugs
Why are oral meds the slowest to be absorbed?
Because of the first pass effect
Morphine, promethazine, Valium, Fenergan
Fat-soluble drugs
More drug in the blood than going where intended
Free drug result
Process by which a drug is transferred from that site of entry into the body to the bloodstream
Absorption
Normal gastric pH
1.4
How many percent of the population do elders make up?
13%
When asking the patient about meds what all do you ask about?
Always ask about prescriptions, OTC, vitamins minerals and herbs
What are the most common drugs prescribed elders?
Psychotropics and anti-inflammatory agents
What affects how the body uses meds, how much blood carrying meds gets to spot to work
Reduced amount of G.I. bloodflow
What contributes to taking a while for med to move from stomach to bloodstream
Slowed G.I. motility
What takes place after drug has been absorbed into bloodstream?
Distribution
What does increase body fat in elderly pose problem for?
Increased body fat increases the ability to store fat soluble drugs can lead to drug toxicity, decreases the drugs elimination from body. Allowing the drug to stay in the body longer.
What affects how drug attaches to protein, increases level of free drug through bloodstream
Decreased serum albumin
What is the change of a drug from its original form to a new form?
Biotransformation