Exam 6 - Meds and the Elderly Flashcards

0
Q

Lasix, NSAIDs, Dilantin…

A

Highly protein-bound drugs

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1
Q

Why are oral meds the slowest to be absorbed?

A

Because of the first pass effect

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2
Q

Morphine, promethazine, Valium, Fenergan

A

Fat-soluble drugs

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3
Q

More drug in the blood than going where intended

A

Free drug result

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4
Q

Process by which a drug is transferred from that site of entry into the body to the bloodstream

A

Absorption

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5
Q

Normal gastric pH

A

1.4

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6
Q

How many percent of the population do elders make up?

A

13%

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7
Q

When asking the patient about meds what all do you ask about?

A

Always ask about prescriptions, OTC, vitamins minerals and herbs

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8
Q

What are the most common drugs prescribed elders?

A

Psychotropics and anti-inflammatory agents

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9
Q

What affects how the body uses meds, how much blood carrying meds gets to spot to work

A

Reduced amount of G.I. bloodflow

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10
Q

What contributes to taking a while for med to move from stomach to bloodstream

A

Slowed G.I. motility

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11
Q

What takes place after drug has been absorbed into bloodstream?

A

Distribution

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12
Q

What does increase body fat in elderly pose problem for?

A

Increased body fat increases the ability to store fat soluble drugs can lead to drug toxicity, decreases the drugs elimination from body. Allowing the drug to stay in the body longer.

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13
Q

What affects how drug attaches to protein, increases level of free drug through bloodstream

A

Decreased serum albumin

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14
Q

What is the change of a drug from its original form to a new form?

A

Biotransformation

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15
Q

Reduced cardiac output leads to

A

Decreased perfusion to the liver

16
Q

What in the elderly can lead to thiamine deficiency?

A

Antacids

17
Q

What reduces folic acid and thiamin in an elderly?

A

Antibiotics and Dilantin

18
Q

What are most drug doses based on

A

A 70 kg adult, about 150 pounds

19
Q

The process of removing a drug or it’s metabolites from the body

A

Excretion

20
Q

The product of drug metabolism

A

Metabolites

21
Q

What does reduced renal bloodflow caused?

A

Loss of nephrons

22
Q

What’s the main source of drug excretion?

A

The kidneys

23
Q

What is the most used OTC med in the elderly?

A

Laxatives

24
Q

Decreased lean muscle mass in the elderly leads to what?

A

The ability to eliminate water soluble drugs from the body. Allowing drugs to stay longer and increase risk for drug toxicity