Exam 2: Health and Disease ( Mycotoxicosis to Repro disease) Flashcards
xMycotoxicosis is the result of
the ingestion of grains or forages containing toxic metabolites produced by certain fungi
fungi that produce toxins do so under what conditions
warm
moist
humid
what are the three main functions affected by mycotoxicosis
metabolic
nutritional
endocrine
what are some things that mycotoxicosis can cause
decreased ADG
decreased repro
liver damage
immunosuppression
predisposes pigs to secondary disease
are older or younger pigs more susceptible to mycotoxicosis
younger
what are the three levels of myctoxicosis
sub-acute: low levels, not very often (most common)
acute: some consuming, low levels
chronic: consuming over long period of time
idea behind Salem witch trials
what is the treatment for mycotoxicosis
none; stop feed
aflatoxicosis
mycotoxins produced by Aspergillus flavus, Aspergillus parasiticus or Penicillium puberulum
fungi found growing on corn, wheat, peanuts, other ceral grains
pigs with subacute aflatoxicosis can experinence
reduced feed intake
poor ADG
poor FE
acute aflatoxicosis is RARE
hemorrhaging
fatty liver (can be condemed)
symptoms of acute aflatoxicosis in pigs can include
ergotism is caused by
fungus Claviceps purpurea
found in grasses and several cereal grains, especially rye, oats and wheat
inhibited mammary development
reduced litter size
reduced birth weights
symptoms of subacute ergotism in sows
symptoms of acute ergotism in recently weaned and finishing pigs
reduced growth weights
tissue necrosis of tail, hooves, ears
gangrenous sloughing of the extremities
symptoms of acute ergotism in pigs (general)
zearlaenone (F-2)
produced by Fusarium graminearum
found in moldy corn, other grains and pelleted cereal feeds.
zearlaenone (F-2) has an estrogenic effect that results in
mammary development in prepuberal gilts and swelling/enlargement of the vulva
what are the two digestive diseases we discussed
Porcine Epidemic Diarrhea (PEDV)
Transmissible Gastroenteritis (TGE)
general info on PEDV
a coronavirus that only occurs in swine
fairly new ~2013 in U.S
not as big as a concern bc of vaccine
closely resembles TGE
transmission of PEDV
fecal-oral route
fomites
**found in feces
what does PEDV do
virus attacks villi of enterocytes on the villi of the SI
in the SI it causes degeneration and necrosis of enterocytes, turning them cuboidal/flat instead of finger-like
failure of intestine to absorb fluid= diarrhea=deydration and depletion of electrolytes
symptoms of PEDV
all ages: watery diarrhea
infected nursery pigs: die after 3-4 days due to dehydration
prevention of PEDV
vaccine
expose preg sows to virus
Transmissible gastroenteritis (TGE)
acute, rapidly spreading viral disease in swine of all ages, characterized by diarrhea and vomiting
a coronavirus
closely related to PEDV
mortality related to TGE
high mortality: pigs less than 2 wks of age
mortality decreases as age increases
what months are mycotoxicosis and TGE worse in
winter
transmission of TGE
fecal-oral route
nasal route
what does TGE do
infect epithelia cells with destruction or loss of function
patch atrophy of intestine villi of the jejunum and ileum
lesions=malabsorbtion
TGE: the inability to breakdown lactose in dam’s milk leads to an
the osmotic flow of fluids into the lumen, resulting in diarrhea and dehydration
symptoms of TGE
vomiting
diarrhea
dehydration
slow growth
shivering
thirst
**pigs tweaked and die with 1-2d
**pigs infected after 4wks can survive
T/F TGE spreads rapidly to affect all susceptible pigs
true