Drugs of Abuse Flashcards

1
Q

All the drugs of abuse share the property of _____________.

A

increasing dopamine delivery to the nucleus accumbens

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2
Q

Why does MDMA lead to electrolyte disturbances?

A

It induces ADH release.

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3
Q

Cross tolerance is common in what drugs of abuse?

A

Benzodiazepines and ethanol

Heroin and other opiates

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4
Q

Yawning, rhinorrhea, lacrimation, and sweating are early signs of _____________ withdrawal.

A

opioid

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5
Q

Rebound hyperexcitability can occur in withdrawal from benzodiazepines. What can you do to treat it?

A

Administer a phenobarbital, benzodiazepine, or buspirone (a partial serotonin agonist) for the anxiety

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6
Q

What is bruxism?

A

The involuntary habit of grinding teeth at night

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7
Q

How can you speed the excretion of cocaine?

A

Acidifying the urine

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8
Q

What is the lethal dose of nicotine?

A

60 mg

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9
Q

What mechanism is the CB1 cannabinoid receptor?

A

Gi

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10
Q

How should you treat CNS stimulant overdose?

A

Give antihypertensives and benzodiazepines

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11
Q

In addition to hyperthermia, hypertension, and agitation, cocaine can also cause ______________.

A

seizures

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