Drugs of Abuse Flashcards
All the drugs of abuse share the property of _____________.
increasing dopamine delivery to the nucleus accumbens
Why does MDMA lead to electrolyte disturbances?
It induces ADH release.
Cross tolerance is common in what drugs of abuse?
Benzodiazepines and ethanol
Heroin and other opiates
Yawning, rhinorrhea, lacrimation, and sweating are early signs of _____________ withdrawal.
opioid
Rebound hyperexcitability can occur in withdrawal from benzodiazepines. What can you do to treat it?
Administer a phenobarbital, benzodiazepine, or buspirone (a partial serotonin agonist) for the anxiety
What is bruxism?
The involuntary habit of grinding teeth at night
How can you speed the excretion of cocaine?
Acidifying the urine
What is the lethal dose of nicotine?
60 mg
What mechanism is the CB1 cannabinoid receptor?
Gi
How should you treat CNS stimulant overdose?
Give antihypertensives and benzodiazepines
In addition to hyperthermia, hypertension, and agitation, cocaine can also cause ______________.
seizures
