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Step 2 DIT Rapid Review > Day 10 - HemOnc3 > Flashcards

Day 10 - HemOnc3 Flashcards

1
Q

Leukemia: most common neoplasm in children

A

ALL

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2
Q

Leukemia: most common neoplasm in adults, avg age of onset 50 yo

A

CLL

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3
Q

Leukemia: Philadelphia chromosome almost always seen

A

CML

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4
Q

Leukemia: Smudge cells on smear

A

CLL

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5
Q

Leukemia: Peripheral blasts, PAS+, TdT+

A

ALL

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6
Q

Leukemia: Peripheral blasts, PAS-, Myeloperoxidase+, Auer rods

A

AML

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7
Q

Leukemia: Pancytopenia in Down syndrome pt

A

ALL

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8
Q

Med assoc w/ remission in 95% of CML pts

A

Imatinib

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9
Q

21 yo p/w recent wt loss, pruritus, night sweats; PE - hepatosplenomegaly, nontender cervical LAD

A

Hodgkin lymphoma

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10
Q

Hematologic neoplasm: Assoc EBV

A

Burkitt Lymphoma

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11
Q

Hematologic neoplasm: Reed-Sternberg cells, cervical LAD, night sweats

A

Hodgkin lymphoma

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12
Q

Hematologic neoplasm: Bence Jones proteins, osteolytic lesions, hypercalcemia

A

Multiple myeloma

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13
Q

Hematologic neoplasm: t(14;18)

A

Follicular lymphoma

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14
Q

Hematologic neoplasm: Most common lymphoma in US

A

Diffuse large b cell

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15
Q

Hematologic neoplasm: t(8;14)

A

Burkitt lymphoma

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16
Q

Hematologic neoplasm: t(9;22)

A

CML (bcr-abl = Philadelphia chromosome); Also 15% adult ALL

17
Q

Hematologic neoplasm: most common form of Hodgkin lymphoma

A

Nodular sclerosis

18
Q

Hematologic neoplasm: Starry sky appearance

A

Due to phagocytosis of apoptotic tumor cells; Burkitt lymphoma

19
Q

Hematologic neoplasm: High Hb & Hct, pruritus (especially after hot shower/bath), burning pain in hands/feet

A

PCV

20
Q

Hematologic neoplasm: blood smear shows hair like projections, splenomegaly

A

Hairy B cell leukemia

21
Q

Anti-retrovirals: lactic acidosis

A

NRTIs

22
Q

Anti-retrovirals: GI intolerance

A

Protease inhibitors

23
Q

Anti-retrovirals: Pancreatitis, Peripheral neuropathy

A

Zalcitabine, Stavudine, Didanosine (i.e., certain NRTIs); Ritonavir (protease inhibitor) also causes only pancreatitis

24
Q

Anti-retrovirals: Megaloblastic anemia

A

Zidovudine (i.e., a NRTI)

25
Q

Anti-retrovirals: Rash

A

NNRTIs

26
Q

Anti-retrovirals: Hyperglycemia, DM, Lipid abnormalities

A

Indinavir, Sequinavir, Amprenavir (i.e., certain Protease inhibitors)

27
Q

Anti-retrovirals: Bone marrow suppression

A

Zidovudine (i.e., a NRTI); recall: also causes megaloblastic anemia

28
Q

Anti-retrovirals: Given to pregnant women w/ HIV

A

Regardless of HAART therapy, can use Zidovudine(i.e., a NRTI) during labor

29
Q

Anti-retrovirals: Recommended for occupational HIV exposure

A

Zidovudine + Lamivudine (i.e., certain NRTIs)

30
Q

Antibx ppx in HIV pts: when, with what, & for what organisms

A

CD4

Step 2 DIT Rapid Review (111 decks)

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