Day 10 - HemOnc1 Quiz Flashcards

1
Q

Teenage Af-Am male p/w right hip pain in ER, Hct 25%

A

Sickle cell pt w/ osteonecrosis of femoral head

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2
Q

Next step - febrile neutropenia 2/2 chemotherapy

A

Admit; Blood cultx, urine cultx, CXR; Broad spectrum IV antibx (cefipime, ceftazidime)

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3
Q

Most common cause of anemia in elderly pts

A

Iron deficiency anemia (may be due to chronic GI blood loss, but most commonly due to decreased iron intake)

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4
Q

Blood smear: anemia 2/2 lead poisoning

A

Microcytic, hypochromic anemia w/ basophilic stippling; possibly, also ringed sideroblasts

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5
Q

Cause of anemia: alcoholic pt w/ elevated MCV

A

Folate deficiency

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6
Q

Cause of anemia: after taking sulfa drug

A

G6PD deficiency

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7
Q

Med long-term mgt sickle cell disease

A

Hydroxyurea (induces HbF formation)

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8
Q

Iron studies w/ Iron deficiency anemia

A

Serum Fe Low, Ferritin Low, Transferrin high; Serum Fe/Transferrin

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9
Q

Lab values in anemia 2/2 hemolysis

A

H + H low, MCV normal (normocytic), High reticulocyte, Elevated unconjugated bilirubin, High LDH, Low Haptoglobin

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10
Q

Schistocytes

A

Hemolytic anemia, DIC, HUS/TTOP

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11
Q

Acanthocytes

A

aka Spur cell; Abetalipoproteinemia

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12
Q

Bite cells

A

G6PD deficiency

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13
Q

Basophilic stippling

A

Lead poisoning; Thalassemia, Alcohol

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14
Q

Peripheral neuropathy, sideroblastic RBCs

A

Lead poisoning

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15
Q

Hypersegmented neutrophils

A

B12 or Folate deficiency

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16
Q

Heinz bodies

A

G6PD deficiency

17
Q

Vaccines particularly important in children w/ Sickle Cell disease

A

Pneumococcal, HiB, Hep B, Influenza

18
Q

Other than vaccination, how prevent pneumococcal infx in children w/ sickle cell

A

ppx penicillin until 5 yo

19
Q

Complication in 10% pts w/ sideroblastic anemia

A

Acute leukemia