Day 10 - HemOnc1 Quiz Flashcards
Teenage Af-Am male p/w right hip pain in ER, Hct 25%
Sickle cell pt w/ osteonecrosis of femoral head
Next step - febrile neutropenia 2/2 chemotherapy
Admit; Blood cultx, urine cultx, CXR; Broad spectrum IV antibx (cefipime, ceftazidime)
Most common cause of anemia in elderly pts
Iron deficiency anemia (may be due to chronic GI blood loss, but most commonly due to decreased iron intake)
Blood smear: anemia 2/2 lead poisoning
Microcytic, hypochromic anemia w/ basophilic stippling; possibly, also ringed sideroblasts
Cause of anemia: alcoholic pt w/ elevated MCV
Folate deficiency
Cause of anemia: after taking sulfa drug
G6PD deficiency
Med long-term mgt sickle cell disease
Hydroxyurea (induces HbF formation)
Iron studies w/ Iron deficiency anemia
Serum Fe Low, Ferritin Low, Transferrin high; Serum Fe/Transferrin
Lab values in anemia 2/2 hemolysis
H + H low, MCV normal (normocytic), High reticulocyte, Elevated unconjugated bilirubin, High LDH, Low Haptoglobin
Schistocytes
Hemolytic anemia, DIC, HUS/TTOP
Acanthocytes
aka Spur cell; Abetalipoproteinemia
Bite cells
G6PD deficiency
Basophilic stippling
Lead poisoning; Thalassemia, Alcohol
Peripheral neuropathy, sideroblastic RBCs
Lead poisoning
Hypersegmented neutrophils
B12 or Folate deficiency