CVS Physiology 9 Flashcards

1
Q

what organ is makly resonisble for the long term control of blood pressure

A

kidneys

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2
Q

what are some functions of the kidenys

A

exertion of waste
maintenace of ion balace
regulation of ph
regulation of osmolarity
reguatoon of plasma volume

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3
Q

what specil part of blood is used to measure map

A

plasma volume

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4
Q

what is the osmoliarty outside the collecting duct

A

very high

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5
Q

what moluece determies the osmolarity gradient in the kidnes

A

na

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6
Q

at what point inthe loop of henie is the concentration of sodium the greateest

A

bottom, due to gravity

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7
Q

what happens if the colletin duct is very water permeable

A

lots of water reabosbrion and little urine produced which conserves plasma volume

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8
Q

what happens if you make htte collecting duct impermeable to water

A

very little reabsorbtion will occur and thus there will be lots of urine and a reduction in plasma volume

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9
Q

what is the renin angiotnsin sterone systme

A

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid and electrolyte balance, and systemic vascular resistance.

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10
Q

where is renis prodiued

A

fro hte juxtaglomerular cells of the kidney (granule cell)

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11
Q

what trigger renein production

A

sympathiect nerves to juxtaglomerular apparatus ( redeuces map
decreadsed distention of the afferent arterioles
decreased delivery of na+/cl-

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12
Q

what is the general effect of renin productoin

A

increase in map

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13
Q

what does renin do

A

converts inactive angiotensinogen to angiotensin 1

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14
Q

what convertes angiotension 1 into angiotension 2

A

angiotensin converting enzyme

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15
Q

what does angiotensin 2 do

A

stimulates the relase of aldrosterone fromthe adreal cortex
stimulares the release of adh
vasco constivtor

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16
Q

what is the fucntion of aldosterone

A

increases na+ reabsorption in the loop of henle
reduces diuresis and increases plasma volume

17
Q

where is adh relased from

A

piturity gland

18
Q

wher is adh symptestied

A

hypothalamus

19
Q

what is the function of adh

A

increases water perijmty to the colllecting duct - increasing plama volume
vascocontriton - increase map
increases sensation of thirst

20
Q

what is the effect of vascocontrictor on the tpr

A

increases it

21
Q

what cuaes hte relaes in adh

A

decre in blood volume - from the cardiopulmonary barocrectpotrs - via delayed meullary cariovascarul centers
an increase in osmolarity of the interstital fluid
circulation angiotension 2

22
Q

anp

A

atrial natriuretic peptide

23
Q

bnp

A

brain natriuretic peptide

24
Q

where is anp and bnp produces

A

myocardia cells in the atria and venticules

25
what triggers the relase of anp and bnp
increasded distension of the artia and venticeles
26
what do anp and bnp do
increse excertio of na+ inhibit the realse of renin act onmedullary cv centres to reduces map
27
what percent of hypertension are secondary
5-10 %
28
what drug basis treamet can be used
ca2+ channel antagoinis b - adrenoreceptor antagaonists thiazide diuretics angiotension converting enzyme inhibitors angiotensin 2 antagonists
29
what is teh role of adh
increase senstion of first, vasoconstior incrase periml yof collecting duct to h20
30
where is adh from
pitarury gland
31
where is adh sympteised
hypothalamus
32
what isthe role of aldosterone
incrases na reaposionin te loop of henle reduces diures and increase palsam voues
33
what isthe treiggers for adh
baro recorprs incrased osmolaity of intersi fludi by osmorecoprots in the hypothalums circulating angiotensin 2
34
what triggers teh reales of aldosteron
alterotensin 2
35
role of anp and bnp
increase eeertio of na inhib rnels of rening act on meuarl to cv centre to reedd map