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Cardiovascular > arrhythmia therapy and drugs > Flashcards

arrhythmia therapy and drugs Flashcards

1
Q

what conditoin are classed as arthymias

A

sinus arrhytmias, bardycardia, tachycardia, superventiuar arrhytmia, atrail fibrillon, svt junutoial, ventralar arrhythmia, vventicalry tachyat, venticlay fibrialoin

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2
Q

class 1 drug type

A

1a - moderase soium channel bloackade
1b - mild soium channel blockdade
1c - strong soidum chnnle blocka
all reduce amplude of ap and condition velocity

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3
Q

example of class 1a

A

quinidine, procainamide, dispyramide

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4
Q

examples of 1b

A

lidocaine, mexiline, tocainde

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5
Q

type of 1c

A

flecaiinde, propafenone

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6
Q

what is type 2

A

b blocker
bdaer recpoat antagoins -0 slow sa disace and av onduoi, shortens phase 4 and stage2

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7
Q

what is class 2 examples

A

atenonl, bisoprolol

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8
Q

what is class 3 examples

A

amiodarone,, bretylium, sotalol

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9
Q

what is class 4 exampels

A

diltiazem, verapamil

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10
Q

what is class 5 examples

A

dioxina, adenosiin

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11
Q

what do class 3 do

A

pronlon reflaion, slow k out of cell , increase aciton potiel durion, prolign replion stage 3

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12
Q

when can class 3 potaium chanel blockers bue used, l

A

life threating ventriular tachycaria or fibrilaion, atrial fibrion or fluttoier restiant to other drugs

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13
Q

what are amiodarmine used for

A

superveniucar tachyarida

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14
Q

what drugs does aminodarone react with

A

digoxin

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15
Q

what are some of the side effects of amiodarone

A

thryois, pulomary firois, slate, corenal deposions, lft abdnomaleis

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16
Q

what drugs are class 4

A

ccb , depres phae 4 depolisoin in sa and av nodes, slow heart rate down, decrease automatoricy shortens phase 2 plu by shorin ca2+

17
Q

what are class 5 drugs o

A

other antiarthy

18
Q

what is eh efect of dioxin

A

increased val tone, increase ca2+

19
Q

what is indicoitn for use of digoxin

A

atrial fibrialion, atrali flutter, svt, heart failure

20
Q

what are signs of diogein toxity

A

nausea and vomitin, xanthopsia, bradycarida, tachycarida, arrhymias, vt and vf

21
Q

wht is the effet of adenosiin

A

bind to the adensio recptr, blocks condiont through av nodes, opens k channesl,, incrase camp levsi which inhigb ca2+
hperpolase the cell to prevent depolases
h

22
Q

what i the reverase agento digoxin

A

digibind

23
Q

how is adensoide admisterd

A

fast pused though iv

24
Q

what are vitamen k angatons

A

warfarin

25
Q

what are directi thromhin inhitor exampoles

A

dabigatran

26
Q

whta are direct xa inhitosr examples

A

apixaban, rivaroxabmn, edoxaban

27
Q

what is thechane in prothbin time when suign warthin

A

up to 2.5- 4 times increase

28
Q

what is the side effedct so warfarin

A

bleeing, interaciton with other drus, pregancy - teratogenic, avoid in 1st and 3d trimesters

29
Q

what is the effect of aspirin and sulfonamides on warfin

A

decreased bining to albumin,increign it activty - albuit decres it bioavialbtiy

30
Q

what is the effect of cimetidein and erythromycin on warfarin

A

inhibis degredation, increasein it acttivty

31
Q

what is the effects of antibiotc oin warfarin

A

decreased symthes of clotting facots, increase ing its actiyt

32
Q

hw does heapring promt bleeing

A

supers clotitng factors

33
Q

what drugs supres warfarin actigy

A

barbituase and pheyoti as p450
vit k - promoe clting factor symtes
cholesytine - reduce absobrion

34
Q

what are direct anticoat

A

apixabn, rivaroxabn, edoxabn

35
Q

drusg which are cytochrme p450 inducters

A

Cytochrome p450 infludcs – alcohol barbiutes, carbanzmein, pheytopin, rifampicin, sulphonylureas

36
Q

drugs which are cytochrome p450 inhibitors

A

omeprazonle
Disulfiram
Erythommycin
Sodium Valproate
Isoniazid
Ciprofloxacin and cimetrine ethanol
sulphonamides

Cardiovascular (37 decks)

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