CVS physiology 7 Flashcards

1
Q

what can a precapilly spinger do

A

close off capialry in response to local signals

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2
Q

What do contius cappilarys have

A

leaky juctions

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3
Q

what do festeraed capily have

A

large pores

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4
Q

what is transcytoiss

A

where the prtein and macromoleues across the endotheleuim

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5
Q

what special function can transodies vessles do

A

fuse thoguher

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6
Q

where are contius cappilres with no clefts often found

A

brain,

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7
Q

where are contiues capilles with clefts often found

A

musles

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8
Q

where are fenestreaed cappilers often found

A

kidnesy and liver and intesties,

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9
Q

what are disconitus

A

wher both clefts and pores are found

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10
Q

where a disconitus cappilers found

A

liver

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11
Q

what is starling forces

A

the difference in hydrostatic pressure and colloid oncotic pressure

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12
Q

where do non polar subasance diffuse across capilaires

A

phospholipid membrane

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13
Q

where do polar subsance diffuse across hte cappilaries

A

clefts/ pores

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14
Q

what is an example of carrier mediated transport

A

glucose to the brain

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15
Q

what is darcys law

A

says that flow = pressure/resitance

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16
Q

what is net filtration pressure equation

A

(hc-hif) - (pic-pif)

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17
Q

what are the two determing factros of startling law

A

capilly hydrostaic pressure vs isf hydrostaic pressure
plasma hydrostaic pressure - isf hydrosatic pressure

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18
Q

how much fluid is lost per day

A

20l

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19
Q

how much fluid is picked up per day

A

17 l

20
Q

what hapens to the remaing fluid

A

it is picked up by the lymp system

21
Q

odema causes

A

rasied cvp , lymphatic obsution, hypoproteinaemia, increased capillary permeability

22
Q

what are causes of cvp

A

ventricular failure

23
Q

what are the caues of lymph obstruciotn

A

filariasis, surgury

24
Q

what is the causes of hypoproteinanemia

A

nephrotic syndrome, liver failure, malnutrition

25
Q

what is the cause of increased capillary permeabilty

A

rhumatism

26
Q
A
27
Q

what is poulie law

A

resisance = (viscoity time lengh times 8)/(radius to the power of 4 times Pi)

28
Q

what is the subsitusio of darcys law and poulines law for flow

A

flow = (pressure times radius to the 4th power times pi)/ n timse l8)

29
Q

what is the equation for mean arterial pressure

A

co times tpr

30
Q

what does local / instinsic smooth musle control incovle

A

indivula organs

31
Q

what does central/ extrinsic smooth musle controla incove

A

ensure that met ot eh towat pherial resiton for the whole body is correct

32
Q

what is local instic controals metablic contraol do

A

hyperameia
this caues a increase in metabolic activity, and an increased in the conc of metabolites
this triggers the release of paracrine singa e.g. edrf or no
this cause arteril dilation
this washes out metabolites
this is an adaption to math blood supply to the metabolic needs of that tissue

33
Q

what is local instics control of pressure / flow reguationin

A

a decrease in perfusoin,
cuaes mean arteiril pressure to rise, decerasing flow,
metabolites accumeualte
thisrelase paracrine signa;
arterioles dialte and flow is restored to normal
this adapton is desired to ensure that the tissue maintain its blood supply despidet changes in map

34
Q

what is reactive hyperaemia

A

a trigger is occulion of blood supply
increased blood flow

35
Q

what is injury respone stages

A

c fiber, then substance p, then mast cell, then histame, this ledas ot arterial dilation and increased blood flow wn

36
Q

what does the nerual contoal innervate

A

parasymphat and sympathi

37
Q

what is the effect of hte nura control sympathic pathway

A

realse rnorlaia, this binds to alpha one recoreps , this leads to arterilar contsion, and decred blood flow through that iisu and incerse tpr and map.

38
Q

what organs are effected by the incresed flow udign parasympathi nerves

A

genitaltia dn slaviary glands

39
Q

what is the effect of b2 recerptors activation on keltela and cartic musles

A

caues arterl dilation, therfore increaed flow through that tiss and decrease tpr

40
Q

when is coronary blood supply interuped

A

systole

41
Q

what function does the heart show during reduced blood supoly

A

hyperaemia

42
Q

what is a special characteristic of cerebral circulation

A

shows excellent presure autoregulaations

43
Q

what is the spection characterist of puoary circulation

A

reduced o2 cause arteilar contstoin to reducire blood to best ventilared parts

44
Q

what is the special characteristic of the renal circulation

A

filtration, ket constant during noraml fluctations in map, excellent pressure autoregulation

45
Q

hyperemaia

A

when there is more blood than normal to the body tissues