Cardiovascular drugs Flashcards
what is meant by cardiovascular disease
ischeamic heart disease e.g. angina and mi
heart failure
cerebrovascular disea e.g. transie ishce attah and thrombotic stoke
hyper tenison
arrhymias e.g. atrial fibulation
Atheroslerosis
damage to vessle wall- smoking, other cause of low grade infmaotr damage
what aues atheroscois
smoking, and wall stress from high bp
what is a stable plaue
large fious cap and small lip coare, n=low maorphage concte an no cap ruprus
what is examples of antiplatelte
aspirin
clopidogrel / ticagrelor p2y12 adp receptors
dipyrideimole phosphodiesterase inhibitrs
gp11b/111a fibriogen receptor antagonists
how does aspirin work
inhibits enzyme cox1 required to produce the presuasess thromboxane a2
hw does clopidogrel and tricagrellor work work
used to block vng to p2y12 adp recprots reudinv the stickiness of platelets
how does dipyrimode work
it s aphosphodiesterase inhibitor stopping the productio of prostacyclin
what aret the side effects of ace inhibtors
cough, orthalstic hpotension
renal inparinte
hypoklameia
what are the side effects of arbs
no cough but orthaostic hypotion
renal imparement
hyperkalemi
aldosterone antaeons effects
renal impairemtn, hyopianateis, hyperkalemai, gnaeoastertia
enestro is made up of what
valsartan and sacubrital
what is sacurbital
neppirysin inhitro, inhibtis the break down of anp and bnp
increase diure , natres and vasoidaion,
indicated in symptoac chroin hf with reduced ejection fractoin
what an enestro not be peried with
ace
sidde effect of dihydopride callcium channel blcoker
postural hypotenion, perhipal oedema, tachy cardia, bardycaria
what is the side effects of non dydorphde ccb
bardycaria, heat block, posteral hypotin, perialyodeam
side effects of satin
musle aches and pain, myoitis `
side effects of thiazine diuretics
electrolyite imbalances
hgyperuricena
hyperglycea
dehyarion, renal impairmet
orthostatic hypotenoin
gout
side effecs ofloop diuretics
elctorlyte distubaces
dehydration adn renal impairment
orthostatic hypotension
side effects of gtn
headace, postuoral hypotension
side effect of nicorandil
headache, posturala hypotensionk and ulceratin in gi gtract
side effects of antihypertensives
peripahl vasoidaltion
what isthe effect of loop dierutics
block nacl in reapboion int he asceng limb of te loop of henle
vaso and veno dilatior effect
what is the effect of thizide diuretics
blockgn nacl reaboion in teh distal co erted tubel of the kidneys
mild diureitc effect
vasodialtion effect
