Coughs and Colds

Question 1

a. Topical oxymetazoline causes rebound congestion if used for more than a week

Answer 1

a. True

Question 2

b. Pseudoephedrine causes drowsiness as an adverse effect

Answer 2

b. False, stimulant causes insomnia

Question 3

c. Codeine splits the disulphide bonds in the protein component of mucous

Answer 3

c. False, acts on the cough centre

Question 4

d. Topical phenylephrine has a longer duration of action than topical oxymetazoline

Answer 4

d. False, phenylephrine is short acting and oxymetazoline is long acting

Question 5

e. Guaiphenesin is an expectorant

Answer 5

e. True

Question 6

a. Pseudoephedrine is a mucolytic agent

Answer 6

a. False, non-slective decongestant

Question 7

b. Codeine causes constipation as an adverse effect

Answer 7

b. True

Question 8

c. Topical oxymetazoline causes rebound congestion if used for more than 5 days

Answer 8

c. True

Question 9

d. Mesna is an anti-tussive agent

Answer 9

d. False, mucolytic (cystic fibrosis)

Question 10

e. Theophylline is a bronchodilator

Answer 10

e. True

Question 11

Adverse effects:

a. Topical phenylephrine: burning sensation

Answer 11

a. True

Question 12

Adverse effects:

b. N-acetylcysteine: bronchodilation

Answer 12

b. False, bronchoconstriction (C/I asthmatics)

Question 13

Adverse effects:

c. Dornase alpha: voice alterations

Answer 13

c. True (mucolytic)

Question 14

Adverse effects:

d. Promethazine: insomnia

Answer 14

d. False, drowsiness

Question 15

Adverse effects:

e. Intranasal fluticasone: nasal bleeding

Answer 15

e. True

Question 16

In the management of cough

a. codeine causes diarrhea

Answer 16

a. False, constipation

Question 17

b. dextromethorphan is a mucolytic agent

Answer 17

b. False, anti-tussive

Question 18

c. guaiphenesin is an expectorant

Answer 18

c. True

Question 19

d. N-acetylcysteine is a cough suppressant

Answer 19

d. False, mucolytic

Question 20

e. codeine is a Mu-opioid receptor agonist

Answer 20

e. True

Question 21

The following drugs are used in the treatment of rhinitis

a. oxymetazoline

Answer 21

a. True

Question 22

The following drugs are used in the treatment of rhinitis

b. fluticasone

Answer 22

b. True

Question 23

The following drugs are used in the treatment of rhinitis

c. propranolol

Answer 23

c. False

Question 24

The following drugs are used in the treatment of rhinitis

d. phenylephrine

Answer 24

d. True

Question 25

The following drugs are used in the treatment of rhinitis | e. pseudoephedrine

Answer 25

e. True

Question 26

Drugs used in the management of coughs and colds | a. oxymetazoline has a longer duration of action than topical phenylephrine

Answer 26

a. true

Question 27

Drugs used in the management of coughs and colds | b. fexofenadine is a histamine-1-receptor antagonist

Answer 27

b. true

Question 28

Drugs used in the management of coughs and colds | c. cyclizine is preferred to loratadine in management of allergic rhinitis

Answer 28

c. false

Question 29

Drugs used in the management of coughs and colds | d. pseudoephedrine causes hypotension as an adverse effect

Answer 29

d. false, hypertension

Question 30

Drugs used in the management of coughs and colds | e. codeine is an expectorant

Answer 30

e. false, antitussive

Question 31

In the treatment of coughs and colds | a. pseudoephedrine causes insomnia as an adverse effect

Answer 31

a. True, stimulant

Question 32

In the treatment of coughs and colds | b. phenylephrine is an alpha-adrenoceptor antagonist

Answer 32

b. False, agonist

Question 33

In the treatment of coughs and colds | c. bromhexine is a mucolytic

Answer 33

c. True

Question 34

In the treatment of coughs and colds | d. N-acetylcysteine cleaves extracellular DNA

Answer 34

d. False, breaks disulphide bonds

Question 35

In the treatment of coughs and colds | e. pseudoephedrine is contraindicated in patients with uncontrolled hypertension

Answer 35

e. True, causes hypertension as an adverse effect

Question 36

A 25 year old man presents to the pharmacy complaining of a blocked nose with accompanying rhinitis. The pharmacist prescribes a topical decongestant for his blocked nose, but warns the man not to use the decongestant for longer than 7 days as it will cause rebound congestion. What is name of this drug?

Answer 36

Oxymetazoline

Question 37

Decongestants and cough medication | a. guaiphenesin is a cough suppressant

Answer 37

a. False, expectorant

Question 38

Decongestants and cough medication | b. pseudoephedrine contraindicated in patients with uncontrolled hypertension

Answer 38

b. True

Question 39

Decongestants and cough medication | c. dornase alfa is used in the treatment of cystic fibrosis

Answer 39

c. True

Question 40

Decongestants and cough medication | d. oxymetazoline causes the presynaptic release of noradrenalin

Answer 40

d. False, inhibits release of NE

Question 41

Decongestants and cough medication | e. pseudoephedrine is safe to use in patients on monoamine oxidase inhibitor therapy

Answer 41

e. False, CI