Coughs and Colds Flashcards
a. Topical oxymetazoline causes rebound congestion if used for more than a week
a. True
b. Pseudoephedrine causes drowsiness as an adverse effect
b. False, stimulant causes insomnia
c. Codeine splits the disulphide bonds in the protein component of mucous
c. False, acts on the cough centre
d. Topical phenylephrine has a longer duration of action than topical oxymetazoline
d. False, phenylephrine is short acting and oxymetazoline is long acting
e. Guaiphenesin is an expectorant
e. True
a. Pseudoephedrine is a mucolytic agent
a. False, non-slective decongestant
b. Codeine causes constipation as an adverse effect
b. True
c. Topical oxymetazoline causes rebound congestion if used for more than 5 days
c. True
d. Mesna is an anti-tussive agent
d. False, mucolytic (cystic fibrosis)
e. Theophylline is a bronchodilator
e. True
Adverse effects:
a. Topical phenylephrine: burning sensation
a. True
Adverse effects:
b. N-acetylcysteine: bronchodilation
b. False, bronchoconstriction (C/I asthmatics)
Adverse effects:
c. Dornase alpha: voice alterations
c. True (mucolytic)
Adverse effects:
d. Promethazine: insomnia
d. False, drowsiness
Adverse effects:
e. Intranasal fluticasone: nasal bleeding
e. True
In the management of cough
a. codeine causes diarrhea
a. False, constipation
b. dextromethorphan is a mucolytic agent
b. False, anti-tussive
c. guaiphenesin is an expectorant
c. True
d. N-acetylcysteine is a cough suppressant
d. False, mucolytic
e. codeine is a Mu-opioid receptor agonist
e. True
The following drugs are used in the treatment of rhinitis
a. oxymetazoline
a. True
The following drugs are used in the treatment of rhinitis
b. fluticasone
b. True
The following drugs are used in the treatment of rhinitis
c. propranolol
c. False
The following drugs are used in the treatment of rhinitis
d. phenylephrine
d. True
The following drugs are used in the treatment of rhinitis
e. pseudoephedrine
e. True
Drugs used in the management of coughs and colds
a. oxymetazoline has a longer duration of action than topical phenylephrine
a. true
Drugs used in the management of coughs and colds
b. fexofenadine is a histamine-1-receptor antagonist
b. true
Drugs used in the management of coughs and colds
c. cyclizine is preferred to loratadine in management of allergic rhinitis
c. false
Drugs used in the management of coughs and colds
d. pseudoephedrine causes hypotension as an adverse effect
d. false, hypertension
Drugs used in the management of coughs and colds
e. codeine is an expectorant
e. false, antitussive
In the treatment of coughs and colds
a. pseudoephedrine causes insomnia as an adverse effect
a. True, stimulant
In the treatment of coughs and colds
b. phenylephrine is an alpha-adrenoceptor antagonist
b. False, agonist
In the treatment of coughs and colds
c. bromhexine is a mucolytic
c. True
In the treatment of coughs and colds
d. N-acetylcysteine cleaves extracellular DNA
d. False, breaks disulphide bonds
In the treatment of coughs and colds
e. pseudoephedrine is contraindicated in patients with uncontrolled hypertension
e. True, causes hypertension as an adverse effect
A 25 year old man presents to the pharmacy
complaining of a blocked nose with accompanying rhinitis. The pharmacist prescribes a topical decongestant for his blocked nose, but warns the man not to use the decongestant for longer than 7 days as it will cause rebound congestion. What is name of this drug?
Oxymetazoline
Decongestants and cough medication
a. guaiphenesin is a cough suppressant
a. False, expectorant
Decongestants and cough medication
b. pseudoephedrine contraindicated in patients with uncontrolled hypertension
b. True
Decongestants and cough medication
c. dornase alfa is used in the treatment of cystic fibrosis
c. True
Decongestants and cough medication
d. oxymetazoline causes the presynaptic release of noradrenalin
d. False, inhibits release of NE
Decongestants and cough medication
e. pseudoephedrine is safe to use in patients on monoamine oxidase inhibitor therapy
e. False, CI
