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Pharm Final > Coughs and Colds > Flashcards

Coughs and Colds Flashcards

1
Q

a. Topical oxymetazoline causes rebound congestion if used for more than a week

A

a. True

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2
Q

b. Pseudoephedrine causes drowsiness as an adverse effect

A

b. False, stimulant causes insomnia

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3
Q

c. Codeine splits the disulphide bonds in the protein component of mucous

A

c. False, acts on the cough centre

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4
Q

d. Topical phenylephrine has a longer duration of action than topical oxymetazoline

A

d. False, phenylephrine is short acting and oxymetazoline is long acting

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5
Q

e. Guaiphenesin is an expectorant

A

e. True

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6
Q

a. Pseudoephedrine is a mucolytic agent

A

a. False, non-slective decongestant

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7
Q

b. Codeine causes constipation as an adverse effect

A

b. True

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8
Q

c. Topical oxymetazoline causes rebound congestion if used for more than 5 days

A

c. True

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9
Q

d. Mesna is an anti-tussive agent

A

d. False, mucolytic (cystic fibrosis)

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10
Q

e. Theophylline is a bronchodilator

A

e. True

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11
Q

Adverse effects:

a. Topical phenylephrine: burning sensation

A

a. True

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12
Q

Adverse effects:

b. N-acetylcysteine: bronchodilation

A

b. False, bronchoconstriction (C/I asthmatics)

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13
Q

Adverse effects:

c. Dornase alpha: voice alterations

A

c. True (mucolytic)

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14
Q

Adverse effects:

d. Promethazine: insomnia

A

d. False, drowsiness

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15
Q

Adverse effects:

e. Intranasal fluticasone: nasal bleeding

A

e. True

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16
Q

In the management of cough

a. codeine causes diarrhea

A

a. False, constipation

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17
Q

b. dextromethorphan is a mucolytic agent

A

b. False, anti-tussive

18
Q

c. guaiphenesin is an expectorant

A

c. True

19
Q

d. N-acetylcysteine is a cough suppressant

A

d. False, mucolytic

20
Q

e. codeine is a Mu-opioid receptor agonist

A

e. True

21
Q

The following drugs are used in the treatment of rhinitis

a. oxymetazoline

A

a. True

22
Q

The following drugs are used in the treatment of rhinitis

b. fluticasone

A

b. True

23
Q

The following drugs are used in the treatment of rhinitis

c. propranolol

A

c. False

24
Q

The following drugs are used in the treatment of rhinitis

d. phenylephrine

A

d. True

25
Q

The following drugs are used in the treatment of rhinitis

e. pseudoephedrine

A

e. True

26
Q

Drugs used in the management of coughs and colds

a. oxymetazoline has a longer duration of action than topical phenylephrine

A

a. true

27
Q

Drugs used in the management of coughs and colds

b. fexofenadine is a histamine-1-receptor antagonist

A

b. true

28
Q

Drugs used in the management of coughs and colds

c. cyclizine is preferred to loratadine in management of allergic rhinitis

A

c. false

29
Q

Drugs used in the management of coughs and colds

d. pseudoephedrine causes hypotension as an adverse effect

A

d. false, hypertension

30
Q

Drugs used in the management of coughs and colds

e. codeine is an expectorant

A

e. false, antitussive

31
Q

In the treatment of coughs and colds

a. pseudoephedrine causes insomnia as an adverse effect

A

a. True, stimulant

32
Q

In the treatment of coughs and colds

b. phenylephrine is an alpha-adrenoceptor antagonist

A

b. False, agonist

33
Q

In the treatment of coughs and colds

c. bromhexine is a mucolytic

A

c. True

34
Q

In the treatment of coughs and colds

d. N-acetylcysteine cleaves extracellular DNA

A

d. False, breaks disulphide bonds

35
Q

In the treatment of coughs and colds

e. pseudoephedrine is contraindicated in patients with uncontrolled hypertension

A

e. True, causes hypertension as an adverse effect

36
Q

A 25 year old man presents to the pharmacy
complaining of a blocked nose with accompanying rhinitis. The pharmacist prescribes a topical decongestant for his blocked nose, but warns the man not to use the decongestant for longer than 7 days as it will cause rebound congestion. What is name of this drug?

A

Oxymetazoline

37
Q

Decongestants and cough medication

a. guaiphenesin is a cough suppressant

A

a. False, expectorant

38
Q

Decongestants and cough medication

b. pseudoephedrine contraindicated in patients with uncontrolled hypertension

A

b. True

39
Q

Decongestants and cough medication

c. dornase alfa is used in the treatment of cystic fibrosis

A

c. True

40
Q

Decongestants and cough medication

d. oxymetazoline causes the presynaptic release of noradrenalin

A

d. False, inhibits release of NE

41
Q

Decongestants and cough medication

e. pseudoephedrine is safe to use in patients on monoamine oxidase inhibitor therapy

A

e. False, CI

Pharm Final (25 decks)

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