Anaemia

Question 1

Anaemia:

a. iron dextran therapy is contraindicated in patients with arthritis

Answer 1

A. False,

Question 2

Anaemia:

b. iron sucrose causes hypotension

Answer 2

B. True, parenteral iron therapy can cause both hypotension and hypertension

Question 3

Anaemia:

c. deferoxamine is used to treat Vitamin B12 overload

Answer 3

C. False, Used to treat acute iron or aluminum toxicity (an excess of aluminum in the body) in certain patients.

Question 4

Anaemia:

d. for maximum absorption, slow-release oral iron preparations are taken after meals

Answer 4

D. False, preferably on an empty stomach, however this maybe intolerable

Question 5

Anaemia:

e. parenteral iron therapy leads to peptic ulcer disease

Answer 5

E. False, because parenteral iron doesn’t pass through the GIT

Question 6

Anaemia

a. vitamin B12 is essential in the treatment of iron deficiency anaemia

Answer 6

a. False, iron deficiency anemia is treated with iron. Pernicious anemia requires B12

Question 7

Anaemia

b. tea reduces the absorption of dietary iron

Answer 7

b. True

Question 8

Anaemia

c. a deficiency in folic acid causes megaloblastic anaemia

Answer 8

c. True, folic acid and B12 deficiencies causes megaloblastic anaemia

Question 9

Anaemia

d. folic acid is used to treat pernicious anaemia

Answer 9

d. False, pernicious anaemia is treated with B12 and supplemented with folic acid

Question 10

Anaemia

e. parenteral iron therapy causes acute hypersensitivity as an adverse effect

Answer 10

e. True

Question 11

Treatment of Anaemia

a. ferrous sulphate causes gastric irritation as an adverse effect

Answer 11

a. True, oral iron solutions cause gastric irritation

Question 12

Treatment of Anaemia

b. megaloblastic anaemia is treated with ferrous sulphate

Answer 12

b. False, megaloblastic anaemia is treated with B12 and folic acid.

Question 13

Treatment of Anaemia

c. vitamin B12 deficiency causes megaloblastic anaemia

Answer 13

c. True,

Question 14

Treatment of Anaemia

d. the use of erythropoietin is allowed in sport

Answer 14

d. False

Question 15

Treatment of Anaemia

e. iron dextran injections causes anaphylaxis

Answer 15

e. True, parenteral iron therapy can cause hypersensitivity reactions. Therefore it is important to test first

Question 16

In the treatment of anaemia

a. folic acid is used as a single agent to treat pernicious anaemia

Answer 16

a. False, pernicious anaemia is caused by a B12 deficiency. Folic acid can partially reverse some of the hematologic abnormalities of Vitamin B12 deficiency, although the neurologic manifestations will progress. Hence, it is important to rule out Vitamin B12 deficiency before treating a patient with megaloblastic anaemia with folic acid

Question 17

In the treatment of anaemia

b. parenteral iron therapy increases the risk of anaphylactic reactions

Answer 17

b. True, must always test first

Question 18

In the treatment of anaemia

c. oral iron supplementation is contraindicated in the management of severe megaloblastic anaemia

Answer 18

c. True, oral iron is contraindicated with preexisting b12/folate deficiency

Question 19

In the treatment of anaemia

d. tea decreases the absorption of iron from the GIT

Answer 19

d. True, tea, antacids, milk decrease absorption of iron

Question 20

In the treatment of anaemia

e. vitamin B12 is administered via the intravenous route

Answer 20

e. False, never IV. Can be oral, parenteral or IM

Question 21

Anaemia

a. erythropoietin abuse increases the risk for thromboembolism

Answer 21

a. True

Question 22

Anaemia

b. used as a single agent, orally administered intrinsic factor reverses pernicious anaemia

Answer 22

b. False, B12 is used to treat pernicious anaemia. Intrinsic factor can be co-administered

Question 23

Anaemia

c. iron supplements reverse the effects of Vitamin B12 deficiency

Answer 23

c. False, iron is CI in a b12 deficiency

Question 24

Anaemia

d. iron supplementation causes gastric distress

Answer 24

d. True

Question 25

Anaemia | e. vitamin B6 deficiency causes sideroblastic anaemia

Answer 25

e. True, but very rare

Question 26

Anaemia | a. Oral ferrous sulphate is contraindicated in patients with peptic ulceration

Answer 26

a. True, will worsen peptic ulceration

Question 27

Anaemia | b. Oral iron therapy is stopped at least 72 hours before parenteral therapy

Answer 27

b. True, need oral iron therapy to have been cleared out of the system

Question 28

Anaemia | c. Iron overload is treated with deferoxamine

Answer 28

c. True

Question 29

Anaemia | d. Parenteral iron causes necrotizing gastroenterising as an adverse effect

Answer 29

d. False, does not pass through GIT

Question 30

Anaemia | e. In pregnancy, iron supplementation is decreased

Answer 30

e. False, increased

Question 31

Anaemia | f. Iron absorption is enhanced by vitamin C

Answer 31

f. True

Question 32

Anaemia | g. Adverse effects of iron are worsened when taken concurrently with food

Answer 32

g. False, for maximal absorption iron is given on an empty stomach but is often not well tolerated. Food will decrease absorption but decrease adverse effects

Question 33

Anaemia | h. Folic acid is used to treat pernicious anaemia

Answer 33

h. False, treat with B12 and folic acid

Question 34

Anaemia | i. Chronic alcohol increases the risk of folic acid deficiency

Answer 34

i. True

Question 35

Anaemia | j. Activated charcoal is an antidote for iron toxicity

Answer 35

j. False, activated charcoal is in my toothpaste

Question 36

Treatment of anaemia | a. Folic acid deficiency increases the risk of microcytic anaemia

Answer 36

a. Megaloblastic anaemia

Question 37

Treatment of anaemia | b. High doses of vitamin C increases B12 absorption

Answer 37

b. False, vitamin c increase iron absorption, intrinsic factor increases b12 absorption