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Pharm Final > Anaemia > Flashcards

Anaemia Flashcards

1
Q

Anaemia:

a. iron dextran therapy is contraindicated in patients with arthritis

A

A. False,

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2
Q

Anaemia:

b. iron sucrose causes hypotension

A

B. True, parenteral iron therapy can cause both hypotension and hypertension

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3
Q

Anaemia:

c. deferoxamine is used to treat Vitamin B12 overload

A

C. False, Used to treat acute iron or aluminum toxicity (an excess of aluminum in the body) in certain patients.

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4
Q

Anaemia:

d. for maximum absorption, slow-release oral iron preparations are taken after meals

A

D. False, preferably on an empty stomach, however this maybe intolerable

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5
Q

Anaemia:

e. parenteral iron therapy leads to peptic ulcer disease

A

E. False, because parenteral iron doesn’t pass through the GIT

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6
Q

Anaemia

a. vitamin B12 is essential in the treatment of iron deficiency anaemia

A

a. False, iron deficiency anemia is treated with iron. Pernicious anemia requires B12

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7
Q

Anaemia

b. tea reduces the absorption of dietary iron

A

b. True

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8
Q

Anaemia

c. a deficiency in folic acid causes megaloblastic anaemia

A

c. True, folic acid and B12 deficiencies causes megaloblastic anaemia

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9
Q

Anaemia

d. folic acid is used to treat pernicious anaemia

A

d. False, pernicious anaemia is treated with B12 and supplemented with folic acid

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10
Q

Anaemia

e. parenteral iron therapy causes acute hypersensitivity as an adverse effect

A

e. True

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11
Q

Treatment of Anaemia

a. ferrous sulphate causes gastric irritation as an adverse effect

A

a. True, oral iron solutions cause gastric irritation

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12
Q

Treatment of Anaemia

b. megaloblastic anaemia is treated with ferrous sulphate

A

b. False, megaloblastic anaemia is treated with B12 and folic acid.

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13
Q

Treatment of Anaemia

c. vitamin B12 deficiency causes megaloblastic anaemia

A

c. True,

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14
Q

Treatment of Anaemia

d. the use of erythropoietin is allowed in sport

A

d. False

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15
Q

Treatment of Anaemia

e. iron dextran injections causes anaphylaxis

A

e. True, parenteral iron therapy can cause hypersensitivity reactions. Therefore it is important to test first

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16
Q

In the treatment of anaemia

a. folic acid is used as a single agent to treat pernicious anaemia

A

a. False, pernicious anaemia is caused by a B12 deficiency. Folic acid can partially reverse some of the hematologic abnormalities of Vitamin B12 deficiency, although the neurologic manifestations will progress. Hence, it is important to rule out Vitamin B12 deficiency before treating a patient with megaloblastic anaemia with folic acid

17
Q

In the treatment of anaemia

b. parenteral iron therapy increases the risk of anaphylactic reactions

A

b. True, must always test first

18
Q

In the treatment of anaemia

c. oral iron supplementation is contraindicated in the management of severe megaloblastic anaemia

A

c. True, oral iron is contraindicated with preexisting b12/folate deficiency

19
Q

In the treatment of anaemia

d. tea decreases the absorption of iron from the GIT

A

d. True, tea, antacids, milk decrease absorption of iron

20
Q

In the treatment of anaemia

e. vitamin B12 is administered via the intravenous route

A

e. False, never IV. Can be oral, parenteral or IM

21
Q

Anaemia

a. erythropoietin abuse increases the risk for thromboembolism

A

a. True

22
Q

Anaemia

b. used as a single agent, orally administered intrinsic factor reverses pernicious anaemia

A

b. False, B12 is used to treat pernicious anaemia. Intrinsic factor can be co-administered

23
Q

Anaemia

c. iron supplements reverse the effects of Vitamin B12 deficiency

A

c. False, iron is CI in a b12 deficiency

24
Q

Anaemia

d. iron supplementation causes gastric distress

A

d. True

25
Q

Anaemia

e. vitamin B6 deficiency causes sideroblastic anaemia

A

e. True, but very rare

26
Q

Anaemia

a. Oral ferrous sulphate is contraindicated in patients with peptic ulceration

A

a. True, will worsen peptic ulceration

27
Q

Anaemia

b. Oral iron therapy is stopped at least 72 hours before parenteral therapy

A

b. True, need oral iron therapy to have been cleared out of the system

28
Q

Anaemia

c. Iron overload is treated with deferoxamine

A

c. True

29
Q

Anaemia

d. Parenteral iron causes necrotizing gastroenterising as an adverse effect

A

d. False, does not pass through GIT

30
Q

Anaemia

e. In pregnancy, iron supplementation is decreased

A

e. False, increased

31
Q

Anaemia

f. Iron absorption is enhanced by vitamin C

A

f. True

32
Q

Anaemia

g. Adverse effects of iron are worsened when taken concurrently with food

A

g. False, for maximal absorption iron is given on an empty stomach but is often not well tolerated. Food will decrease absorption but decrease adverse effects

33
Q

Anaemia

h. Folic acid is used to treat pernicious anaemia

A

h. False, treat with B12 and folic acid

34
Q

Anaemia

i. Chronic alcohol increases the risk of folic acid deficiency

A

i. True

35
Q

Anaemia

j. Activated charcoal is an antidote for iron toxicity

A

j. False, activated charcoal is in my toothpaste

36
Q

Treatment of anaemia

a. Folic acid deficiency increases the risk of microcytic anaemia

A

a. Megaloblastic anaemia

37
Q

Treatment of anaemia

b. High doses of vitamin C increases B12 absorption

A

b. False, vitamin c increase iron absorption, intrinsic factor increases b12 absorption

Pharm Final (25 decks)

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