Anaemia Flashcards
Anaemia:
a. iron dextran therapy is contraindicated in patients with arthritis
A. False,
Anaemia:
b. iron sucrose causes hypotension
B. True, parenteral iron therapy can cause both hypotension and hypertension
Anaemia:
c. deferoxamine is used to treat Vitamin B12 overload
C. False, Used to treat acute iron or aluminum toxicity (an excess of aluminum in the body) in certain patients.
Anaemia:
d. for maximum absorption, slow-release oral iron preparations are taken after meals
D. False, preferably on an empty stomach, however this maybe intolerable
Anaemia:
e. parenteral iron therapy leads to peptic ulcer disease
E. False, because parenteral iron doesn’t pass through the GIT
Anaemia
a. vitamin B12 is essential in the treatment of iron deficiency anaemia
a. False, iron deficiency anemia is treated with iron. Pernicious anemia requires B12
Anaemia
b. tea reduces the absorption of dietary iron
b. True
Anaemia
c. a deficiency in folic acid causes megaloblastic anaemia
c. True, folic acid and B12 deficiencies causes megaloblastic anaemia
Anaemia
d. folic acid is used to treat pernicious anaemia
d. False, pernicious anaemia is treated with B12 and supplemented with folic acid
Anaemia
e. parenteral iron therapy causes acute hypersensitivity as an adverse effect
e. True
Treatment of Anaemia
a. ferrous sulphate causes gastric irritation as an adverse effect
a. True, oral iron solutions cause gastric irritation
Treatment of Anaemia
b. megaloblastic anaemia is treated with ferrous sulphate
b. False, megaloblastic anaemia is treated with B12 and folic acid.
Treatment of Anaemia
c. vitamin B12 deficiency causes megaloblastic anaemia
c. True,
Treatment of Anaemia
d. the use of erythropoietin is allowed in sport
d. False
Treatment of Anaemia
e. iron dextran injections causes anaphylaxis
e. True, parenteral iron therapy can cause hypersensitivity reactions. Therefore it is important to test first
In the treatment of anaemia
a. folic acid is used as a single agent to treat pernicious anaemia
a. False, pernicious anaemia is caused by a B12 deficiency. Folic acid can partially reverse some of the hematologic abnormalities of Vitamin B12 deficiency, although the neurologic manifestations will progress. Hence, it is important to rule out Vitamin B12 deficiency before treating a patient with megaloblastic anaemia with folic acid
In the treatment of anaemia
b. parenteral iron therapy increases the risk of anaphylactic reactions
b. True, must always test first
In the treatment of anaemia
c. oral iron supplementation is contraindicated in the management of severe megaloblastic anaemia
c. True, oral iron is contraindicated with preexisting b12/folate deficiency
In the treatment of anaemia
d. tea decreases the absorption of iron from the GIT
d. True, tea, antacids, milk decrease absorption of iron
In the treatment of anaemia
e. vitamin B12 is administered via the intravenous route
e. False, never IV. Can be oral, parenteral or IM
Anaemia
a. erythropoietin abuse increases the risk for thromboembolism
a. True
Anaemia
b. used as a single agent, orally administered intrinsic factor reverses pernicious anaemia
b. False, B12 is used to treat pernicious anaemia. Intrinsic factor can be co-administered
Anaemia
c. iron supplements reverse the effects of Vitamin B12 deficiency
c. False, iron is CI in a b12 deficiency
Anaemia
d. iron supplementation causes gastric distress
d. True
Anaemia
e. vitamin B6 deficiency causes sideroblastic anaemia
e. True, but very rare
Anaemia
a. Oral ferrous sulphate is contraindicated in patients with peptic ulceration
a. True, will worsen peptic ulceration
Anaemia
b. Oral iron therapy is stopped at least 72 hours before parenteral therapy
b. True, need oral iron therapy to have been cleared out of the system
Anaemia
c. Iron overload is treated with deferoxamine
c. True
Anaemia
d. Parenteral iron causes necrotizing gastroenterising as an adverse effect
d. False, does not pass through GIT
Anaemia
e. In pregnancy, iron supplementation is decreased
e. False, increased
Anaemia
f. Iron absorption is enhanced by vitamin C
f. True
Anaemia
g. Adverse effects of iron are worsened when taken concurrently with food
g. False, for maximal absorption iron is given on an empty stomach but is often not well tolerated. Food will decrease absorption but decrease adverse effects
Anaemia
h. Folic acid is used to treat pernicious anaemia
h. False, treat with B12 and folic acid
Anaemia
i. Chronic alcohol increases the risk of folic acid deficiency
i. True
Anaemia
j. Activated charcoal is an antidote for iron toxicity
j. False, activated charcoal is in my toothpaste
Treatment of anaemia
a. Folic acid deficiency increases the risk of microcytic anaemia
a. Megaloblastic anaemia
Treatment of anaemia
b. High doses of vitamin C increases B12 absorption
b. False, vitamin c increase iron absorption, intrinsic factor increases b12 absorption
