CONNECTIVE TISSUE (Lecture 5) Flashcards

1
Q

main functions of connective tissue

A
  • structural framework of the body
  • conducts and translates muscle contractions into movement
  • forms stroma (structural framework) of glands and organs
  • the site of fat and mineral storage
  • site of metabolic exchange
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2
Q

Characteristics of the CT

A
  • low cell density
  • extensive ECM
    - varies w/ functional demands, lots of specialized kinds
  • highly vascular
  • most retain stem/mitotic cells
  • aids in tissue growth / regeneration
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3
Q

composition of CT

A
  • cells (few)
  • ECM
    • ground substance
    • fibers (collagen, elastin)
      -collagen
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4
Q

what type of collagen in the most common

A

type one

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5
Q

characteristic of type 1 collagen

A

highest tensile strength

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6
Q

type of collagen that is composed of slender fibrils found in cartilage

A

type II collagen

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7
Q

type of collagen made of reticular fibers, functions to filter fluid

A

type III collagen

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8
Q

do elastic fibers branch

A

no

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9
Q

example of a cell that originate in and then permanently resides in CT

A

fibroblasts

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10
Q

example of cells that develop somewhere else then migrate into CT to perform their functions (most cells do develop elsewhere then move into CT)

A

host defense, WBCs, mast cells, macrophages, plasma cells, leukocytes

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11
Q

fibrocytes are ______ derived and transform in tissues into _______

A

fibrocytes are BONE MARROW derived and transform into FIBROBLASTS

fibrocytes (lnactive) –> fibroblasts (active)

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12
Q

elastin fibers usually accompany ______

A

collagen

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13
Q

elastic fiber makeup and characteristics

A

made of a core of elastin surrounded by a sheath of microfibrils
- impact elasticity and tensile strength

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14
Q

2 types of adipocytes

A

unilocular (white fat)
multilocular (brown fat)

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15
Q

Unilocular (white fat) characteristics/function

A
  • white, spheroid cells
  • Synthesize and store fat as a SINGLE lipid inclusion
  • signet ring appearance
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16
Q

Multilocular (brown fat) characteristics/function

A
  • fat stored in MULTIPLE lipid inclusions
  • have more mitochondria
  • heat production
    *found in infant mammals
17
Q

long-living cells that originate in bone marrow then migrate out, usually involved in host defense

A

macrophages (clean up crew)
**precursors are monocytes

18
Q

macrophages develop from precursors, ________

A

monocytes

19
Q

transient cell

A

express the foreign gene but do not integrate it into their genome
ex: plasma cells

20
Q

function, location, and characteristics of plasma cells

A
  • Synthesize and secrete antibodies
  • found in GI and respiratory tract
  • eccentric nucleus (off to the side of cell)
  • lots of w/ euchromatin (active DNA)
21
Q

4 general types of connective tissue

A
  1. Loose
  2. Dense
    - dense irregular
    - dense regular
  3. Adipose
  4. Reticular
22
Q

type of CT that is:
- sparse, loosely arranged fibers, ‘open’
- has an abundance of ground substance

A

Loose (areolar) CT

23
Q

type of CT that is:
- primarily beneath the epithelium
-the primary site of immune and inflammatory reactions

A

Loose (areolar) CT

24
Q

type of CT that
- has an abundance of bundled fiber, ‘compact’
- little ground substance
- regular or irregular
- directionality of tensile strength

A

Dense CT

25
Q

type of CT?

A

irregular dense CT (disorganized)

26
Q

type of CT?

A

regular dense “box car nuclei’, wavy appearance

27
Q

what is the stripping pattern of collagen fibrils called?

A

periodicity

28
Q

fibrils are bound into _____ which are then bound into ______

A

fibers then tendon

29
Q

reticular as a term

A

latticework

30
Q

how does brown fat (multilocular) generate heat w/out needing to shiver

A

having tons of mitochondria