Chapter 5 Flashcards
Integumentary System Functions
Protection from physical, chemical, microorganisms, and radiation Regulate body temperature Excretion Produce Vitamin D Sensory Reception
Keratinocytes
Most abundant cell type of epidermis
Produce keratin
Keratin
Tough protein in epidermis that strengthens cells and helps provide protection
Melanocytes
Produce melanin
Tactic Epithelial Cells “Merkel”
Convey information to sensory neurons
Touch receptors
Dendritic cells “Langerhans”
Macrophages that have immune functions
Undergo endocytosis
Layers of epidermis
(Deep) Stratum Basale Stratum Spinosum Stratum Granulosum Stratum Lucidum Stratum Corneum (Superficial)
Stratum Basale
Deepest layer of epidermis
Attached to dermis
1 layer of actively dividing cells
Cell types- Keratinocytes, Merkel cells, Melanocytes
Stratum Spinosum “Spiny layer”
2nd deepest layer of epidermis
Gets name from spiny appearance on histology slides
Cells- Keratinocytes and Dendritic cells
Stratum Granulosum
3rd deepest layer of epidermis
Last living layer
Keratohyaline granules- Help form more keratin
Lamellated granules- Secrete waterproofing glycolipid
Cells- Keratinocytes
Stratum Lucidum
4th deepest layer of epidermis
Only present in thick skin of palms and soles of feet
Few layers of flat, dead keratinocytes
Stratum Corneum
Most superficial layer of skin
Thick layer of dead keratinocytes
Provides protection from abrasion and penetration
Thickens to form calluses
Papillary Dermis
Top 20% of dermis
Contains dermal papillae
Dermal Papillae
Projections into epidermis that increase Surface Area
Function: Promote diffusion and adhere epidermis to dermis
Blisters
Caused when stratum basale and papillary dermis separate and fluid gets between them