chapter 20 Flashcards

1
Q

two compounds of blood

A

plasma (liquid matrix) and formed elements (everything inside the plasma which is erythrocyte, leukocyte and platlets)

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2
Q

hypovelemic

A

low blood volume

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3
Q

hypervelemic

A

excessive blood/plasma volume

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4
Q

plasma

A

55% of blood, made of 92% water, 7% protein 1% other stuff

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5
Q

plasma proteins

A

albumins, globulins, fibrogen

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6
Q

formed elements

A

everything but plasma

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7
Q

plasma v intersitital fluid

A

plasma has more dissolved oxygen and less carbon dioxide (diffuses out of tissue)
-interstitial fluid does not have dissolved tissue but plasma does

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8
Q

albumin

A

contribute to osmotic pressure, smalles protein

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9
Q

fibrogen

A

largest protein and helps clotting

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10
Q

immunoglobulins

A

antibodies

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11
Q

hematocrit

A

packed cell volume

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12
Q

rbc structure

A

-bioconcave disc
-thin central region
-lack organelles and nucleus

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13
Q

rbc no nucleus

A

let it travelt hrough circulation and be flexible

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14
Q

rbc lack mitochondria

A

mitochondria use oxygen to make atp and without it oxygen can be transported instead of being used

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15
Q

what transports oxygen and carbon dioxide?

A

hemoglobin

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16
Q

hemoglobin

A

-four polypeptide subunits that each contain a molecule of heme (porphyrin ring/ iron ion ring)
-iron binds to the oxygen and the polypeptide unit binds to co2

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17
Q

cabon monoxide

A

competes with the heme ring for binding sites which makes it dangerous bc lack of oxy and ppl die

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18
Q

blood type

A

-determined by antigen on cell surface
-antigen= agglutinogens (glycoproteins or glycolipids)
-three types of agglutinogens (a b and d)

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19
Q

o type blood

A

both a or b angglutinogen

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20
Q

a type

A

b agglutinin antibody in plamsa

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21
Q

b type

A

a agglutinin in plasma which is why they can not receive a blood, the a agglutinin has antibodies against a

22
Q

ab type

A

neither agglutinin

23
Q

agglutinin

A

causes clumping

24
Q

universal recipient

A

ab type (rarest also)

25
Q

leukocytes

A

-granulocytes or agranulocytes
-short life span
-diapedesis

26
Q

granulocytes

A

-neutrophils, eosinophils and basophils

27
Q

agranulocytes

A

-monocytes and lymophocytes

28
Q

leukopenia

A

low leukocyte count

29
Q

leukocytosis

A

high leuk count

30
Q

differential count

A

determines which leuk is in excess or too low

31
Q

diapedisis

A

leukocytes crawl out of capillaries into the tissue

32
Q

chemotaxis

A

tells leukocytes where to go through chemotactic agents

33
Q

neutrophils

A

kill bacteria
-first wbc at the site
-phagocytic
-multilobes nucleus

34
Q

eosinophils

A

-reduce inflammation
-allergic reaction
-bilobed nucleus

35
Q

basophils

A

-histamine and heparin
-cold, allergy, runny nose (histamine)
-heparin (prevents blood clotting)
-hidden nucleus

36
Q

monocytes

A

-large and phagocytic
-attract fibroblasts and other phagocytes
-kidney nucleus

37
Q

fibroblasts

A

produce collagen at the infected site
-collagen makes scar tissue

38
Q

lymphocyte

A

-t, b, or natural killer
-large nucleus
-viral infections

39
Q

t cells

A

attack foreign cells

40
Q

b cells

A

secrete antibodies to attack foreign cells

41
Q

natural killers

A

immune surveillance

42
Q

platlets

A

-come from megakaryocytes
-megakaryocyte= platelet thromboplastin factor

43
Q

thrombocytopenia

A

-low thrombocytes
-cause spontaneous bleeding over mouth, skin and anus

44
Q

thrombocytosis

A

-high thrombocytes
-clump into clots

45
Q

function of platelets

A

-clotting (hemostasis)
-release platelet htormboplastin factor
-form plug
-actin and myosin that contract the clot

46
Q

hemopoiesis

A

-blood formation
-begin with pluripotential stem cells
-myeloid and lymphoid stem cells
myeloid becomes erythrocytes, plastelets and everything but lymphocytes

47
Q

step by step formation erythro

A

-myeloid cell, progenitor cell, proerythroblast, erythroblast, reticulocyte and erythrocyte

48
Q

plastelet step by step

A

-myeloid to progenitor to megakeryoblast to platelet

49
Q

leuokocyte step by step

A

myeloid, progenitor, meyloblast and monoblast, myelocyte, promonocytes, then banded cells, segmented cells to basophil, eosinophil or neutrophil
-monocyte comes right from promonocyte

50
Q

step by step wbc

A

lympohoid, lymphoblast, prolymohocyte, lymphocytes, b, t or nk