Ch 5 Flashcards
What does it mean to be amphipathic and give an example
Both hydrophobic and hydrophilic regions
Ex: phospholipids + membrane proteins
What are lipid rafts
Proteins associated in specialized patches of lipids
Membranes are held together mainly by __
Hydrophobic interactions
Fluid mosaic model function
Acts for passage of things into and out of cell and communication between cells
Some proteins are immobile; what does immobile mean?
Attached top cytoskeleton or extracellular matrix
Membrane fluidity depends on __
Temp and saturation of fatty acid chains
Difference between unsaturated tails and saturated in membrane fluidity
Unsaturated = prevent packing
Saturated = tails pack together
Function of cholesterol in fluidity
Reduces fluidity at high temperature
Decreases temp for solidification
Fluidity Modulation: At lower temperatures, cholesterol prevents the fatty acid chains of phospholipids from packing too closely together, thus maintaining fluidity. At higher temperatures, it can help to restrain excessive movement, preventing the m
How do lipid composition vary with colder and higher temp
Colder = more unsaturated phopholipids
Higher = unique lipids which decrease fluidity
Embedded at least partially in hydrophobic region ___
Integral proteins
Bound to the surface of the membrane
Peripheral proteins
Membrane protein functions (6)
- Intercellular joining
- Attach to cytoskeleton and extracellular matrix
- Enzymatic activity
- Signal transduction
- Cell-cell recognition
- Transport
Short branched carbohydrate chains used to create
Glycoplipids and glycoproteins
Glycolipid and glycoproteins functions
- Sort cells into tissues and organs
- Recognition of self vs non-self: immune system
Membrane layers differ in (2 things)
- Lipid composition
- Direction of inserted proteins
Where and when is the arrangement of membrane lipids and proteins determined
During synthesis in the ER and GA
Selective permeability meaning
Allow passage of some substance, but not others
Is it easy for nonpolar molecules to dissolve in lipid bilayer and why
Yes
Nonpolar molecules share similar chemical properties with the lipid tails of the phospholipids, allowing them to integrate seamlessly into the bilayer. T
How are ions and polar dissolve in lipid bilayer
Water crosses slowly and larger molecules even more slowly
Meaning of passive transport
DOES not use energy
How does substance concentration move in passive transport
High concentration to low
What is the difference between diffusion and osmosis
Diffusion = movement of particles
Osmosis = movement of water
Dynamic equilibrium meaning
Equal movement in either direction across membrane
How does the movement of diffusion differ from osmosis in regards to concentration gradient
Diffusion = move from high to low region
Osmosis = move from high (low solute) water to low (high solute) water concentration
Tonicity meaning
Ability of soln to cause cells to gain or lose water
Tells us what happens to cell when they are put in different solution
3 diff solution in tonicity
- Isotonic
- Hypertonic
- Hypotonic