CH 13 BLOOD SYSTEM DEFINITIONS Flashcards
basophil, granulocytes
responds to allergens; releases histamine and heparin
eosinophil, granulocyte
responds to parasitic infections and is a phagocyte in allergic reactions
neutrophil, granulocyte
major role in fighting bacterial infection; phagocyte
lymphocyte, mononuclear
controls the immune response; makes antibodies to antigens
monocyte, mononuclear
phagocytic cell that becomes a macrophage and digests bacteria and tissue debris
albumin
major protein in blood; maintains the proper amount of water in the blood
antibody (Ab)
specific protein (immunoglobulin) produced by lymphocytes in response to bacteria viruses and other antigens. an antibody is specific to an antigen and inactivates it
antigen
foreign substance or toxin that stimulates the production of an antibody
basophil
white blood cell containing granules that stain blue with basic dye, associated with release of histamine and heparin
bilirubin
orange yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells are destroyed
coagulation
blood clotting
colony-stimulating factor
(CSF) protein factor that stimulates the growth and differentiation of developing blood cells. examples are granulocyte CSF, erythropoietin, and thrombopoietin
differentiation
change in structure and function of a cell as it matures; specialization
electrophoresis
method of separating serum proteins by electrical charge and size
eosinophil
white blood cell containing granules that stain red; associated with allergic reactions
erythroblast
immature red blood cell
erythrocyte
red blood cell. there are about 5 million per microliter or cubic millimeter of blood
erythropoietin (EPO)
hormone secreted by the kidneys; stimulates red blood cell formation
fibrin spiderwebs
protein that forms the basis of a blood clot
fibrinogen
plasma protein that is converted to fibrin in the clotting process
globulin
plasma protein; alpha, beta, and gamma (immune) globulins are examples
granulocyte
white blood cell with cytoplasmic granules; eosinophil, neutrophil, and basophil
hematopoietic stem cell
cell in the bone marrow that gives rise to all types of blood cells
hemoglobin
blood protein containing iron’ carries oxygen in red blood cells
heparin
anticoagulant found in blood and tissue cells
immune reaction
response of the immune system to foreign invasion
immunoglobin
protein (a globulin) with antibody activity; examples are IgG, IgM, IgA, IgE, IgD. immun/o means protection
leukocyte
white blood cell
lymphocyte
mononuclear leukocyte that produces antibodies to fight disease
macrophage
monocyte that migrates from the blood to tissue spaces. as a phagocyte, it engulfs foreign material and debris. in the liver, spleen, and bone marrow, macrophages destroy worn out red blood cells and also engulf bacteria and other harmful organisms
megakaryocyte
large platelet precursor cell found in the bone marrow
monocyte
leukocyte with one large nucleus. it is a cell that engulfs foreign material and debris. monocytes become macrophages as they leave the blood and enter body tissues.
mononuclear
pertaining to a cell (leukocyte) with a single round nucleus’; lymphocytes and monocytes are mononuclear leukocytes
myeloblast
immature bone marrow cell that gives rise to granulocytes
neutrophil
granulocytic leukocyte formed in the bone marrow; it is a phagocytic tissue-fighting cell; also called polymorphonuclear leukocyte
plasma
liquid portion of blood, contains water, proteins, salts, nutrients, wastes, lipids, hormones, and vitamins
plasmapherisis
removal of plasma from withdrawn blood, collected cells are re-transfused back into the donor. fresh-frozen plasma or salt solution is used to replace withdrawn plasma.
platelet
small blood cell fragment that collects at sites of injury to begin the clotting process
polymorphonuclear
pertaining to a white blood cell with a multilobed nucleus; neutrophil
prothrombin
plasma protein; converted to thrombin in the clotting process
reticulocyte
immature erythrocyte; a network (reticulum) of strands is seen after staining the cell with special dyes
Rh factor
antigen on red blood cells of Rh-positive (Rh+) individuals. the factor was first identified in the blood of a rhesus monkey
serum
plasma minus clotting proteins and cells. clear, yellowish fluid that separates from blood when it is allowed to clot. it is formed from plasma, but does not contain protein-coagulation factors
stem cell
unspecialized cell that gives rise to mature, specialized forms. a hematopoietic stem cell is the progenitor for all different types of blood cells.