Cellular Injury Flashcards

1
Q

How many layers are there of structural organisation?

A

SIX

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2
Q

What are the different levels of organisation?

CCTOSO

A

Chemical
Cellular
Tissue
Organs
Systems
Organism

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3
Q

How many body systems are there?

A

11

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4
Q

What are the different body systems

A

Integumentary
Skeletal
Muscular
Nervous
Endocrine
Cardiovascular
Lymphatic
Respiratory
Digestive
Urinary
Reproductive

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5
Q

“The maintenance of a relatively stable internal environment regardless of external changes” is what?

A

Homeostasis

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6
Q

What is pathology

A

Study of disease / the structure of a disease

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7
Q

What are the 4 causes of cellular injury?

A

Hypoxia
Toxins
Infectious agents
Physical injury

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8
Q

What causes cellular change?

A

Stressors
Injury

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9
Q

What are the two responses of the cell to stressors called?

A

Adaptation
Death

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10
Q

Are cellular changes reversible or irreversible?

A

Both

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11
Q

Is it hormonal or environmental stimuli that cause cellular change?

A

Both

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12
Q

What is atrophy?

A

Decrease in the size of a cell

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13
Q

What is hypertrophy?

A

Increase in the size of a cell

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14
Q

What is hyperplasia?

A

Increase in number of cells

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15
Q

What is metaplasia?

A

A change in the type of cell

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17
Q

What are the two cellular responses to stressors?

A

Adaptation
Death

18
Q

Is it hormonal or environmental stimuli that cause cellular change?

19
Q

Are cellular changes reversible or irreversible?

20
Q

What is atrophy?

A

The decrease in the size of cell

21
Q

What is hypertrophy?

A

An increase in the size of cell

22
Q

What is hyperplasia?

A

Increase in number of cells.
(for example they may double).

23
Q

What is metaplasia?

A

A change in the type of cell.
(For example, they may get skinnier and become cilia cells).

24
Q

What is dysplasia?

A

A change in the type of cell. (For example, arrangement of the cell, abnormal architecture.

25
What is neoplasia?
New growth of cells
26
What is apoptosis?
Controlled cell death
27
What are the stages of apoptosis?
1.The cell shrinks and chromatin condenses. 2.Membrane starts breaking and organelle disintegrate. 3.Nucleus and organelle collapse, membrane continues to break. 4.Apoptotic bodies form. 5.Macrophages eat apoptotic bodies.
28
What is necrosis?
Uncontrolled cell death
29
What are the stages of necrosis?
1.Organelles swell. 2.Plasma membrane rupture, cellular and nuclear lysis cause inflammation. 3.Phagocytosis
30
What are the differences between apoptosis and necrosis?
Necrosis- Swelling Leakage of cell content. Apoptosis- Shrinkage Nuclear fragmentation Apoptotic bodies No leakage of cell content.
31