Anti coagulants

Question 1

What are the three types of anti coagulant medications?

Answer 1

Vitamin K antagonists
Direct oral anti coags
Low molecular weight heparins

Question 2

What are vitamin K antagonists?

Answer 2

Antagonist = against vitamin K

Question 3

What is the most commonly prescribed anti coagulant?

Answer 3

Warfarin

Question 4

What conditions are vitamin K antagonists likely to be prescribed for?

Answer 4

Heart valve replacement surgery
AF
Deep vein thrombosis
Pulmonary embolism

Question 5

What are Direct oral anti-coagulants (DOACs)

Answer 5

The intrinsic & the extrinsic clotting cascade come together at factor X.

These all prevent factor X from becoming active.

Question 6

How many anti coags are there licensed for use in the UK and how many of those are DOAC’s?

Answer 6

There are 5 anti coags licensed for use in the UK, 4 of which are DOAC’s

Question 7

What are the DOAC’s that prevent factor X from becoming active?

Answer 7

Apixaban
Edoxaban
Ribaroxaban

Question 8

What are all of the DOAC’s

Answer 8

Apixaban
Edoxaban
Ribaroxaban

Dabigatran stops factor II from being activated

Question 9

What is heparin?

Answer 9

There are many types of heparin in many
differing dosages.

Fragmin© used in the community by district
nurse team prefilled syringes - refrigerated.

Commonly for diagnosed DVT or PE.

Heparin works by boosting
anti thrombin x1000