Cell Respiration Flashcards
exchange of gases in the environment
respiration
describe the route of transport of oxygen from the outside to the inside of your body
lungs > blood stream > tissues > cells > mitochondria
reaction in which energy is absorbed
endergonic
modified nucleotide
adenosine triphosphate
How many times can an ATP molecule release energyt
twice
3 major steps in cellular respiration
glycolysis
krebs cycle
electron transport chain
glucose is broken down
glycolysis
takes place in the cytoplasm
anaerobic respiration
6-c glucose is converted to what
2 molecules of pyruvates (3-C)
oxygen is not yet needed
anaerobic
the cell has to utilize ATP to start the process
energy investment phase
production of 4 ATPs
energy payoff phase
net yield of glycolysis
2 ATPs
concentrate the energy into the bonds of ATP
reactions in catabolic pathways
convenient energy carrier
ATP
generally has “high-energy” and unstable bonds
ATP
similar to a highly flammable liquid such as kerosene, which is easier to ignite and provides heat more quickly and convenient
ATP
unstable bond part of ATP that provide the cell with readily available energy for anabolic (synthetic) reactions
“high-energy” molecule
Two general aspects of energy production:
oxidation-reduction mechanisms
ATP generation mechanisms
ATP generation mechanisms include
Oxidative or electron transport level phosphorylation
substrate level phosphorylation
photophosphorylation
ATP is composed of what
nucleoside (adenosine, ribose)
3 phosphate
in this, energy in organic molecules is extracted when they transfer 2 hydrogen atoms
oxidation
hydrogen composed of 2 electrons and protons
2 hydrogen atoms
composed of 2 electrons and protons
coenzyme NAD
Coenzyme NAD+ - receives 1 electron (-) hence, it is reduced and cancels its + charge; and one hydrogen atom making it
NADH
a more energy-rich molecule
NADH
the remaining of this is released to the environment
Hydrogen ion
Every NAD+ that is reduced to NADH, what happens to the extra H+
an extra H+ is released in the process
used by cells in catabolism to extract energy in the form of electrons from nutrient molecules
redox reactions
take nutrients as energy sources and degrade them from highly reduced compounds to fully oxidized compounds
cells
converted to pyruvic acid after a series of steps in glycolysis
glucose
said to have been oxidized along with the reduction of NAD+ electron carriers, among others
glucose
where the reduced electron carriers will proceed to convert energy from the electrons to ATP
Electron transport level phosphorylation
generated in several ways in the cells during respiration, and also during photosynthesis
ATP
also known as oxidative phosphorylation owing to the oxidation-reduction that follows along the electron transport chain
ETLP
in ETLP, this is generated when the electrons from the carriers (e.g. NADH) are carried forward and tossed to the ETC simultaneous with the transport of H+ to the other side of the membrane
ATP
NAD
(Nicotinamide adenine dinucleotide)
FAD
(flavin adenine dinucleotide)
represent the oxidized form of electron carriers
NAD and FAD
NAD and FAD accept a pair of electrons and hydrogen atoms and get converted to their reduced forms
NADH and FADH2
was built after the movement of H+ ions into the other side of the membrane
concentration gradient
as this receives and passes on electrons, they too become reduced and oxidized in the process
ETC
last to receive the de-energized electrons (hence, aerobic respiration)
oxygen
formed when the de-energized electrons couples with the oxygen
water
allows the passive movement of H+ concentration gradient, the energy of the flow is then used to synthesize ATP from ADP and phosphate
ATP synthase
SLP
Substrate Level Phosphorylation
in this mechanism, ATP is usually generated when a high-energy phosphate is directly transferred from a phosphorylated compound to ADP
SLP
this must have gotten its phosphate from an earlier reaction where a substrate must have been oxidized in its favor
phosphorylated compound
this happens in cells during photosynthesis’ light-dependent reactions
photosynthesis
this happens in cells during photosynthesis’ light-dependent reactions
light energy
where the molecules’ electrons jump from one
to another, an ETC similar to that in respiration
carrier proteins
in photophosphorylation, the energy of electrons is used by this to pass along protons (H+) and these are allowed to flow back just like in oxidative phosphorylation
ETC
involves a pathway from the complete breakdown of glucose to carbon dioxide and water
cell respiration
Three major steps of cell respiration
glycolysis
krebs cycle
ETC
glycolysis is divided into two parts
energy investment phase
energy payoff phase
requiring the investment of 2 ATPs
energy investment phase
generates 4 ATPs through substrate-level phosphorylation
Energy payoff phase
net product produced in glycolysis
2 ATP
in glycolysis is very important especially when oxygen becomes short in supply
SLP
cells wherein oxygen can become short in supply
muscle cells
muscle cells rely on this during rapid contraction, and oxygen delivery to tissues cannot supply the requirement of ETLP
glycolysis
accumulates in the tissues and is later metabolized in the liver
lactic acid
after strenuous activity repays the oxygen debt that has occurred
rapid breathing
converts the pyruvate into acetyl-CoA
preparatory step
enters the Krebs Cycle or Citric Acid cycle
Acetyl-CoA
at the end of the Krebs Cycle, this much ATP are produced by SLP
2 ATPs
in step 3, these from the first two steps (glycolysis and krebs cycle) are tossed to the ETC
reduced carriers
in step 3, generates 34 ATPs
ETC
total amount of ATPs per glucose molecule produced
36-38 ATPs
how many ATP is consumed in the energy investment phase in glycolysis
2 ATP
how many ATP is produced through SLP in the energy payoff phase in glycolysis
4 ATP
how many NADH is produced in oxidative phosphorylation the glycolytic pathway
2 NADH
how many ATP can be produced from 1 NADH
3 ATP
how many ATPs can be produced in the glycolytic pathway with 2 NADH
6 ATP
how many ATP is produced in the Krebs Cycle through SLP
2 ATP
is the entry source of energy in glycolysis
glucose
are invested in the energy investment phase to fulfill the conversion of the molecules to PGAL or DHAP
2 ATPs
are inconvertible
PGAL and DHAP
PGAL
3-phosphoglyceraldehyde
DHAP
dihydroxyacetone phosphate
also known as PGAL, can enter the second phase of glycolysis
3-glyceraldehyde phosphate
how many ATPs are produced in the second phase of glycolysis
4 ATPs
in this phase in glycolysis, oxidizes intermediate substrates
energy payoff phase
how many NADH is produced in the energy payoff phase of glycolysis
2 NADH
translated into 3 ATP by ETLP at the ETC
NADH
end product of glycolysis
2 pyruvic acid/pyruvates
is also called the tricarboxylic acid (TCA) cycle or citric acid cycle
Krebs cycle
series of biochemical reactions that releases large amount of potential energy in acetyl coA in step by step manner
krebs cycle
the reaction that happens in the Krebs cycle wherein the electrons are transferred to electron carriers
redox reaction
just like in glycolysis, the carriers take the electrons to the ETC for ATP conversion
carriers
in Krebs cycle, are recycled and it can go on continuously as long as the entry molecules, enzymes, and intermediates are available
intermediates
pyruvic acid is converted into this in the Krebs cycle
acetyl
the Acetyl is attached to this
coenzyme A (CoA)
pyruvic loses this due to decarboxylation
carbon molecule
major outcomes of the krebs cycle
release of CO2 molecules (decarboxylation)
oxidation-reduction reactions to transfer electron to carriers
SLP
carried by the blood to the lungs and is liberated to the atmosphere through exhalation
CO2
(fully stripped of its energy and oxidized to CO2)
decarboxylated
from the previous steps are carried forward and tossed to the ETC while simultaneously transporting H+ to the other side of the membrane using the energy of the electrons
NADH
receiving and passing on the electrons along its length
electron transport complexes