cancer Flashcards

1
Q

pediatric differences

A
  • normal cells are growing faster

- immature function of immune system

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2
Q

normal cells are growing faster which leads to…

A
  • faster growing cancers

- worse side effects

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3
Q

childhood cancer manifestations

A
  • pain
  • muscle wasting
  • anemia
  • infection
  • bruising
  • neurologic symptoms
  • palpable mass
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4
Q

cancer diagnostics

A
  • CBC w dffrntl
  • bone marrow asprtn
  • imaging
  • biopsy
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5
Q

cancer therapy

A
  • surgery
  • chemo
  • radiation
  • bone marrow/hematopoietic stem cell transplantation
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6
Q

cancer surgery

A

completely remove, debulk, explore, biopsy

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7
Q

how can parents ID problems early?

A
  • fever
  • malaise
  • mild respiratory infection
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8
Q

parents need to learn how to care for….

A

central line

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9
Q

tumor lysis syndrome

A

rapid cell death released intracellular contents into bloodstream
»hyper-K

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10
Q

septic shock

A

circulatory failure + hypotension

>cause inadeq tissue perfusion

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11
Q

septic shock

may have inadequate ____ + nonfunctioning _____

A

neutrophil production

granulocytes

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12
Q

treat septic shock w…

A

abx

incr perfusn

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13
Q

space occupying lesions can cause…

A

vena cava syndrome

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14
Q

chemo side effects

A
  • bone marrow suppression
  • n/v
  • anorexia + wt loss
  • oral ulcers
  • constipation
  • pain
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15
Q

bone marrow suppression

onset + duration

A
  • starts 7-10 dys after admin

- lasts 3-4 wk

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16
Q

bone marrow suppression

therapy

A
  • low microbe diet

- use masks

17
Q

nausea + vomiting

onset + duration

A
  • may occur immediately

- lasts up to 48 hr

18
Q

nausea + vomiting

therapy

A
  • antiemetics

- mild exercise

19
Q

anorexia + wt loss

may be possibly seondary to…

A

mucositis

20
Q

anorexia + wt loss

therapy

A

TPN if diet change doesnt work

-pay attention to preferences

21
Q

oral ulcers

manifestation

A

mucositis fr chemo usually occurs w/in 3-4 days

22
Q

oral ulcers

therapy

A

antifungal to less candidal risk

  • good oral hygiene w soft foam wand
  • water irrigation
23
Q

constipation

therapy

A
  • stool softnr
  • laxtv
  • high fiber diet
24
Q

pain

therapy

A
  • opioid
  • NSAID
  • EMLA for accesing port
  • nonpharm methods
25
Q

acetaminophen may mask…

A

fever

26
Q

hematopoietic stem cell transplantation

A

first 7-10 days of chemo

-IV infusion takes about 2-4wk to implant

27
Q

hematopoietic stem cell

manifestations

A
  • pancytopenia lasts several wk

- high risk for anemia, bleeding, graft-vs-host

28
Q

brain tumor

A

-most common solid tumor in kids

29
Q

brain tumor

manifestations

A

-abnormal gait
-change in vision or hearing
-mental status change
»>educatnl + behavrl changes

30
Q

brain tumor

____ is not recommended bc _____

A

chemo

bc limited by BBB

31
Q

brain tumor

prognosis

A

often left w permanent sequelae

  • -slowed dvlpt
  • -incoordination

-esp in kids 3yo or younger

32
Q

neuroblastoma

_____ is common

A

lymph node metastasis

33
Q

neuroblastoma

stage 1

A
  • localized

- confined to area of origin

34
Q

neuroblastoma

stage 2

A
  • unilateral tumor

- ipsilateral + contralateral lymph nodes negative

35
Q

neuroblastoma

stage 2B

A
  • ipsilateral lymph nodes POSITIVE

- contralateral lymph nodes negative

36
Q

neuroblastoma

stage 3

A
  • tumor infiltrating across midline
  • unilateral tumor w contralateral lymph nodes involved
  • midline tumor w bilateral lymph node involved
37
Q

neuroblastoma

stage 4

A

disseminated to distant sites

38
Q

neuroblastoma

stage 4S

A

disseminated to liver, skin, or bone marrow