Biology Chapter 11: The Musculoskeletal System (2 Stars) Flashcards
There are three main types of muscle: skeletal muscle, smooth muscle, and _____ muscle.
cardiac
Skeletal muscle is involved in support and movement, propulsion of blood in the venous system, and thermoregulation. It appears striated, is under voluntary (somatic) control, is _______, and can be divided into red (slow-twitch) fibers that carry out oxidative phosphorylation and white (fast-twitch) fibers that rely on anaerobic metabolism.
polynucleated
Smooth muscle is in the respiratory, reproductive, cardiovascular, and digestive systems. It appears ______, is under involuntary (autonomic) control, and is uninucleated. It can display myogenic activity, or contraction without neural input.
nonstriated
Cardiac muscle comprises the contractile tissue of the heart. It appears striated, is under involuntary (autonomic) control, and is uninucleated (sometimes binucleated). It can also display myogenic activity. Cells are connected with intercalated discs that contain _______
gap junctions
The ______ is the basic contractile unit of striated muscle.
sarcomere
Sarcomeres are made of thick (_____) and thin (____) filaments.
(myosin)
actin
____ and tropomyosin are found on the thin filament and regulate actin–myosin interactions.
Troponin
The _______ can be divided into different lines, zones, and bands.
sarcomere
The boundaries of each sarcomere are defined by _______
Z-lines.
The _____ is located in the middle of the sarcomere.
M-line
The I-band contains only ____ filaments.
thin filaments.
The _____ consists of only thick filaments.
H-zone
The _____ contains the thick filaments in their entirety. It is the only part of the sarcomere that maintains a constant size during contraction.
A-band
Sarcomeres attach end-to-end to become myofibrils, and each myocyte (muscle cell or muscle fiber) contains many ______
myofibrils.
Myofibrils are surrounded by the______ , a calcium containing modified endoplasmic reticulum, and the cell membrane of a myocyte is known as the sarcolemma.
sarcoplasmic reticulum
A system of ______ is connected to the sarcolemma and oriented perpendicularly to the myofibrils, allowing the incoming signal to reach all parts of the muscle.
T-tubules
Muscle contraction begins at the ______ , where the motor neuron releases acetylcholine that binds to receptors on the sarcolemma, causing depolarization.
neuromuscular junction
This depolarization spreads down the sarcolemma to the _______, triggering the release of calcium ions.
T-tubules
____ binds to troponin, causing a shift in tropomyosin and exposure of the myosin-binding sites on the actin thin filament.
Calcium
Shortening of the sarcomere occurs as _____ heads bind to the exposed sites on ____, forming cross bridges and pulling the actin filament along the thick filament, resulting in contraction. This is known as the sliding filament model.
myosin heads
actin
The muscle relaxes when ______ is degraded by acetylcholinesterase, terminating the signal and allowing calcium to be brought back into the SR. ATP binds to the myosin head, allowing it to release from actin.
acetylcholine