B4 Infection and Immunity Flashcards
What is the consequence of a patient getting the wrong blood type during a transfusion?
Acute haemolytic reaction
What is an acute haemolytic reaction?
Circulating antibodies bind to RBCs and cause agglutination
What antibodies are responsible for targeting non-present ABO antigens?
IgM (Naturally occuring)
Which white blood cells are phagocytic?
Neutrophils
Eosinophils
Basophils
Monocytes
What percentage of white blood cells do neutrophils occupy?
70%
What is the lifespan of neutrophils?
5.4 days
At the site of inflammation, what is the lifespan of neutrophils?
1-2 days
Other than phagocytosis, how else do neutrophils kill pathogens?
Releasing granules containing toxic components
What are the main signs of inflammation?
Heat
Redness
Swelling
Pain
What is the term used to describe a matured neutrophil?
Segmented
What is responsible for connecting the lobules in a neutrophil?
Chromatin
How can neutrophilic bands be identified?
The nuclei are horseshoe or drumstick shaped
What are neutrophilic bands?
Immature neutrophils - a step away from becoming mature
What is the term used to describe a cell that has a kidney shaped nucleus but is not capable of division?
Neutrophilic metamyelocyte
What is a neutrophilic myelocyte?
A cell arising from progranulocytes
Contains differentiated granules and a nucleus with compact chromatin
