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Pharmacology > Antiprotozoal Drugs > Flashcards

Antiprotozoal Drugs Flashcards

1
Q

Blood schizonticides

A

Chloroquine

Quinine

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2
Q

Gametocides

A

Primaquine

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3
Q

Sporonticides

A

Proguanil

Pyrimethamine

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4
Q

May precipitate porphyria

A

Chloroquine

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5
Q

Used for chloroquine-resistant malaria

A

Quinine
Atovaquone-Proguanil
Sulfadixine-Pyrimethamine

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6
Q

Used for severe falciparum malaria

A

Quinidine

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7
Q

Causes cinchonism, hemolysis in G6PD deficiency, and blackwater fever

A

Quinine

Quinidine

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8
Q

DOC for malaria in pregnant patients

A

Quinine

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9
Q

Chemoprophylaxis in chloroquine-resistant areas

A

Mefloquine

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10
Q

Used for acute attacks of falciparum malaria

A

Quinine

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11
Q 
Used for the radical cure of P. vivax ans P. ovale
Terminal prophylaxis (vivax, ovale)
A

Primaquine

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12
Q

Chemoprophylaxis for multi drug resistant malaria

A

Doxycycline

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13
Q

Causes tooth enamel dysplasia/discoloration

A

Doxycyline

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14
Q

Can cause nightmares

A

Halofantrine

Lumefrantine

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15
Q

Cardiotoxic (prolongs PR and QT interval)

A

Halofantrine

Lumefrantine

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16
Q

DOC for uncomplicated falciparum malaria in the Philippines

A

Artemeter-Lumefrantine

17
Q

Malaria chemoprophylaxis for chloroquine-sensitive areas

A

Chloroquine 500mg/tab, 1 tab weekly

18
Q

Malaria chemoprophylaxis for chloroquine-resistant areas

A

Mefloquine 250mg/tab, 1 tab weekly

19
Q

Malaria chemoprophylaxis for MDR areas

A

Doxycycline 100mg/tab, 1 tab daily

20
Q

Areas of MDR malaria

A

Palawan
Davao del Norte
Compostella Valley

21
Q

Tissue schizonticides

A

Primaquine

22
Q

Tissue amebicides

A

Chloroquine
Emetines
Metronidazole
Tinidazole

23
Q

Luminal amebicides

A

Diloxanide furoate
Iodoquinol
Paromomycin

24
Q

DOC for asymptomatic carrier of E. histolytica

A

Diloxanide furoate

25
Q

Amebicide which causes thyroid enlargement

A

Iodoquinol

26
Q

DOC for severe intestinal and extraintestinal amebiasis

A

Metronidazole

27
Q

Causes metallic taste, dark urine, and disulfiram reaction

A

Metronidazole

28
Q

Amebicide which causes congenital deafness

A

Paromomycin

29
Q

DOC for cryptosporodiosis

A

Nitazoxanide

30
Q

Drug of choice for prophylaxis and treatment of pneumocystosis

A

Co-trimoxazole

31
Q

Drug of choice for prophylaxis and treatment of toxoplasmosis

A

Pyrimethamine+Clindamycin

32
Q

DOC for advanced west african sleeping sickness

A

Eflornithine

33
Q

DOC for african sleeping sickness

A

Melarsoprol

34
Q

DOC for Chagas disease

A

Nifurtimox

35
Q

DOC for leishmaniasis

A

Sodium stibogluconate

36
Q

First line drug for early west african sleeping sickness

A

Pentamidine

37
Q

First line drug for early east african sleeping sickness

Pharmacology (31 decks)

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