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Pharmacology > Antihelmithic Drugs > Flashcards

Antihelmithic Drugs Flashcards

1
Q

DOC for E. granulosus

A

Albendazole

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2
Q

DOC for ascariasis, ancylostoma, necator, and capillariasis

A

Albendazole

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3
Q

DOC for trichuris

A

Mebendazole

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4
Q

DOC for enterobius

A

Pyrantel pamoate

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5
Q

DOC for strongyloides

A

Ivermectin

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6
Q

DOC for wuchereria and brugia

A

DEC

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7
Q

DOC for trichinella

A

Thiabendazole

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8
Q

DOC for hydatid disease

A

Albendazole

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9
Q

Drug of choice for filariasis and eye worm disease

A

DEC

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10
Q

May cause Mazzotti reaction

A

DEC

Ivermectin

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11
Q

DOC for roundworm and hookworm infections

A

Pyrantel pamoate

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12
Q

Praziquantel is contraindicated in?

A

Ocular Cysticercosis

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13
Q

Contraindicated in pregnancy

A

Mebendazole
Ivermectin
Thiabendazole

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14
Q

DOC for all cestodes except E. granulosus

A

Praziquantel

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15
Q

MOA of praziquantel

A

Increases membrane permeability to calcium, causing marked contraction initially and then paralysis of trematode and cestode muscles; this is followed by vacuolization and parasite death

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16
Q

MOA of pyrantel pamoate

A

Stimulates nicotinic receptors present at neuromuscular junctions of nematodes

17
Q

MOA of mebendazole

A

Selectively inhibits microtubule synthesis and glucose uptake in nematodes

18
Q

MOA of ivermectin

A

Intensifies GABA-mediated neurotransmission in nematodes and causes immobilization of parasites

19
Q

MOA of DEC

A

Immobilizes microfilariae

20
Q

MOA of albendazole

A

Inhibits microtubule assembly

Pharmacology (31 decks)

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