Antibiotic Resistance And Healthcare Associated Infections Flashcards
What is mass spectrometry and when is it used
Ms is a lab technique used to identify chemical compounds by assessing the mass to charge ratio
What are antimicrobial agents
Natural products and chemically synthesis products that target enzymes or bacteria structures
What is the most common target for antibiotics
Bacterial cell wall such as peptidocyglan
What are the other targets of antibodies
Ribosomes
Enzyme for DNA replication
What is antimicrobial resistance
The lack of effect of an antimicrobial in a patient with previous bacteria
How to we prevent antibacterial resistance
Use less antibiotics
Antibiotic stewardship
What are the 2 sited of action of antibiotics
Cell wall and membrane
Nucleic acid synthesis
Protein synthesis
How do we measure antimicrobial resistance
Measure the MIC : minimum inhibitory concentration for the microbe against different antibiotics
And/or
Detect resistance mutation by PCR
