Anti-infective / Micro - Pharma

Question 1

Directly kill microorganism (Irreversible)

Answer 1

Batericidal

Question 2

Inhibits growth of microorganisms (reversible)

Answer 2

Bacteriostatic

Question 3

Most common cause of drug allergies
most common sign: Rashes

Answer 3

Penicillin

Question 4

drug that has cross-allergenicity to Penicillin

Answer 4

Cephalosporin

Question 5

Drug that causes red-man syndrome (sudden, profound decrease BP with or without maculopapular rash)

Answer 5

Vancomycin

Question 6

Responsible for protein synthesis

Answer 6

Ribosomes

Question 7

Drug that causes tooth staining

Answer 7

Tetracycline

Question 8

6 months preg. to 9yr old is not indicated to what drug

Answer 8

Tetracycline

Question 9

Anti-TB drug that causes ototoxicty - CNVIII

Answer 9

Streptomycin

Question 10

Drug that causes pseudomembranous colitis

Answer 10

Clindamycin (Clostridium Difficile)

Question 11

Drug that causes GI Irritation

Answer 11

Erythromycin

Question 12

Bone marrow suppression, Aplastic Anemia, Gray baby synd. is an adverse effect of drug

Answer 12

Chloramphenicol

Question 13

drug that cause Steven Johnson’s syndrome

Answer 13

Sulfonamide

Question 14

What is the most common clinical cause of bacterial resistance to antibiotic

Answer 14

The use of antibiotic when it is not indicated

Question 15

Probenecid is used for
(enhances the effect of Penicillin, increases the excretion of uric acid)

Answer 15

Gouty Arthritis

Question 16

Penicillin G is administered
“Benzathine Penicillin”

Answer 16

IM / IV

Question 17

Penicillin V is administered
“Phenoxymethyl Penicillin”

Answer 17

Orally
(Vivig)

Question 18

Most extended spectrum of Penicillin

Answer 18

Carbenicillin

Question 19

DOC for maxillofacial infection

Answer 19

Penicillin

Question 20

Normal flora of the skin

Answer 20

Staphlycoccus Aureus

Question 21

Most commonly used generation of cephalosporin used in dentistry

Answer 21

3rd Generation

Question 22

DOC for gonorrhea

Answer 22

Ceftriaxone

Question 23

Fluoroquinolones & Tetracycline causes

Answer 23

Photosensitivity

Question 24

Tetracycline is used for Localized Aggressive Periodontitis because

Answer 24

high concentration in GCF & Plasma

Question 25

Aminoglycoside "tetracycline" a anti TB drug that causes

Answer 25

Ototoxicity and Nephrotoxicity

Question 26

Aminoglycosides attacks

Answer 26

Gram Negative Aerobic Microorganism

Question 27

Drug that causes cholestatic hepatitis

Answer 27

MACROLIDES (Erythromycin)

Question 28

dose antibiotic prophylaxis Amoxicillin in adult

Answer 28

2000mg = 2gm

Question 29

dose antibiotic prophylaxis Amoxicillin in Pedo/children

Answer 29

50mg/kg

Question 30

dose antibiotic prophylaxis clindamycin in adult

Answer 30

600mg

Question 31

dose antibiotic prophylaxis clindamycin in pedo/children

Answer 31

20mg/kg

Question 32

antibiotic given allergic to penicillin

Answer 32

Clindamycin

Question 33

Fungi is an Eukaryotic cell that contain

Answer 33

both RNA and DNA

Question 34

DOC for Histoplasma capsulatum a most common systemic fungal infection

Answer 34

Amphotericin B

Question 35

Most toxic of all antifungals

Answer 35

Amphotericin B

Question 36

Amphotericin B is administered/given

Answer 36

IV

Question 37

DOC for Candidiasis: Oral, esophageal, corneal, conjunctival.

Answer 37

Nystatin

Question 38

Swish and swallow, not used for systemic fungal infection

Answer 38

Nystatin

Question 39

doc for Systemic Candidiasis

Answer 39

Amphotericin B or with Azoles

Question 40

Most toxic antifungal

Answer 40

Amphotericin B.

Question 41

Most toxic among Azoles

Answer 41

Ketoconazole (Nizoral)

Question 42

Aspergillus microorganism has a ___ that leads to cancer

Answer 42

Aflatoxin

Question 43

DOC for Aspergillus, backup for Candidiasis

Answer 43

Itraconazole

Question 44

drug that Flows/Crosses to Blood brain barrier, DOC for cryptococcal meningitis

Answer 44

Fluconazole

Question 45

DOC for Tinea, Dermatophytosis (Skin Fungal infection)

Answer 45

Terbinafine

Question 46

Important for inflammatory response

Answer 46

Histamine

Question 47

Major source of Histamine

Answer 47

Mast Cell

Question 48

DOC for Herpes

Answer 48

Acyclovir IV - Nephrotoxicity Oral - GI

Question 49

Amantadine an antiviral drug that can be used in neurological disorder -

Answer 49

Parkinson's Disease

Question 50

Which antiviral drug is effective for Parkinson's disease

Answer 50

Amantadine

Question 51

HAART

Answer 51

Highly active anti retroviral therapy (HIV Positive)

Question 52

MO that causes subgingival caries

Answer 52

Bacteriodes Melaninogenicus

Question 53

Anti-TB drug

Answer 53

R. I. P - most important E. S.