Anti-infective / Micro - Pharma Flashcards
Directly kill microorganism (Irreversible)
Batericidal
Inhibits growth of microorganisms (reversible)
Bacteriostatic
Most common cause of drug allergies
most common sign: Rashes
Penicillin
drug that has cross-allergenicity to Penicillin
Cephalosporin
Drug that causes red-man syndrome (sudden, profound decrease BP with or without maculopapular rash)
Vancomycin
Responsible for protein synthesis
Ribosomes
Drug that causes tooth staining
Tetracycline
6 months preg. to 9yr old is not indicated to what drug
Tetracycline
Anti-TB drug that causes ototoxicty - CNVIII
Streptomycin
Drug that causes pseudomembranous colitis
Clindamycin (Clostridium Difficile)
Drug that causes GI Irritation
Erythromycin
Bone marrow suppression, Aplastic Anemia, Gray baby synd. is an adverse effect of drug
Chloramphenicol
drug that cause Steven Johnson’s syndrome
Sulfonamide
What is the most common clinical cause of bacterial resistance to antibiotic
The use of antibiotic when it is not indicated
Probenecid is used for
(enhances the effect of Penicillin, increases the excretion of uric acid)
Gouty Arthritis
Penicillin G is administered
“Benzathine Penicillin”
IM / IV
Penicillin V is administered
“Phenoxymethyl Penicillin”
Orally
(Vivig)
Most extended spectrum of Penicillin
Carbenicillin
DOC for maxillofacial infection
Penicillin
Normal flora of the skin
Staphlycoccus Aureus
Most commonly used generation of cephalosporin used in dentistry
3rd Generation
DOC for gonorrhea
Ceftriaxone
Fluoroquinolones & Tetracycline causes
Photosensitivity
Tetracycline is used for Localized Aggressive Periodontitis because
high concentration in GCF & Plasma
Aminoglycoside “tetracycline” a anti TB drug that causes
Ototoxicity and Nephrotoxicity
Aminoglycosides attacks
Gram Negative Aerobic Microorganism
Drug that causes cholestatic hepatitis
MACROLIDES (Erythromycin)
dose antibiotic prophylaxis Amoxicillin in adult
2000mg = 2gm
dose antibiotic prophylaxis Amoxicillin in Pedo/children
50mg/kg
dose antibiotic prophylaxis clindamycin in adult
600mg
dose antibiotic prophylaxis clindamycin in pedo/children
20mg/kg
antibiotic given allergic to penicillin
Clindamycin
Fungi is an Eukaryotic cell that contain
both RNA and DNA
DOC for Histoplasma capsulatum a most common systemic fungal infection
Amphotericin B
Most toxic of all antifungals
Amphotericin B
Amphotericin B is administered/given
IV
DOC for Candidiasis: Oral, esophageal, corneal, conjunctival.
Nystatin
Swish and swallow, not used for systemic fungal infection
Nystatin
doc for Systemic Candidiasis
Amphotericin B or with Azoles
Most toxic antifungal
Amphotericin B.
Most toxic among Azoles
Ketoconazole (Nizoral)
Aspergillus microorganism has a ___ that leads to cancer
Aflatoxin
DOC for Aspergillus, backup for Candidiasis
Itraconazole
drug that Flows/Crosses to Blood brain barrier, DOC for cryptococcal meningitis
Fluconazole
DOC for Tinea, Dermatophytosis (Skin Fungal infection)
Terbinafine
Important for inflammatory response
Histamine
Major source of Histamine
Mast Cell
DOC for Herpes
Acyclovir
IV - Nephrotoxicity
Oral - GI
Amantadine an antiviral drug that can be used in neurological disorder -
Parkinson’s Disease
Which antiviral drug is effective for Parkinson’s disease
Amantadine
HAART
Highly active anti retroviral therapy (HIV Positive)
MO that causes subgingival caries
Bacteriodes Melaninogenicus
Anti-TB drug
R. I. P - most important
E. S.