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DMD > Anti-infective / Micro - Pharma > Flashcards

Anti-infective / Micro - Pharma Flashcards

1
Q

Directly kill microorganism (Irreversible)

A

Batericidal

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2
Q

Inhibits growth of microorganisms (reversible)

A

Bacteriostatic

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3
Q

Most common cause of drug allergies
most common sign: Rashes

A

Penicillin

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4
Q

drug that has cross-allergenicity to Penicillin

A

Cephalosporin

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5
Q

Drug that causes red-man syndrome (sudden, profound decrease BP with or without maculopapular rash)

A

Vancomycin

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6
Q

Responsible for protein synthesis

A

Ribosomes

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7
Q

Drug that causes tooth staining

A

Tetracycline

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8
Q

6 months preg. to 9yr old is not indicated to what drug

A

Tetracycline

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9
Q

Anti-TB drug that causes ototoxicty - CNVIII

A

Streptomycin

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10
Q

Drug that causes pseudomembranous colitis

A

Clindamycin (Clostridium Difficile)

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11
Q

Drug that causes GI Irritation

A

Erythromycin

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12
Q

Bone marrow suppression, Aplastic Anemia, Gray baby synd. is an adverse effect of drug

A

Chloramphenicol

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13
Q

drug that cause Steven Johnson’s syndrome

A

Sulfonamide

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14
Q

What is the most common clinical cause of bacterial resistance to antibiotic

A

The use of antibiotic when it is not indicated

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15
Q

Probenecid is used for
(enhances the effect of Penicillin, increases the excretion of uric acid)

A

Gouty Arthritis

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16
Q

Penicillin G is administered
“Benzathine Penicillin”

A

IM / IV

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17
Q

Penicillin V is administered
“Phenoxymethyl Penicillin”

A

Orally
(Vivig)

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18
Q

Most extended spectrum of Penicillin

A

Carbenicillin

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19
Q

DOC for maxillofacial infection

A

Penicillin

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20
Q

Normal flora of the skin

A

Staphlycoccus Aureus

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21
Q

Most commonly used generation of cephalosporin used in dentistry

A

3rd Generation

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22
Q

DOC for gonorrhea

A

Ceftriaxone

23
Q

Fluoroquinolones & Tetracycline causes

A

Photosensitivity

24
Q

Tetracycline is used for Localized Aggressive Periodontitis because

A

high concentration in GCF & Plasma

25
Q

Aminoglycoside “tetracycline” a anti TB drug that causes

A

Ototoxicity and Nephrotoxicity

26
Q

Aminoglycosides attacks

A

Gram Negative Aerobic Microorganism

27
Q

Drug that causes cholestatic hepatitis

A

MACROLIDES (Erythromycin)

28
Q

dose antibiotic prophylaxis Amoxicillin in adult

A

2000mg = 2gm

29
Q

dose antibiotic prophylaxis Amoxicillin in Pedo/children

A

50mg/kg

30
Q

dose antibiotic prophylaxis clindamycin in adult

A

600mg

31
Q

dose antibiotic prophylaxis clindamycin in pedo/children

A

20mg/kg

32
Q

antibiotic given allergic to penicillin

A

Clindamycin

33
Q

Fungi is an Eukaryotic cell that contain

A

both RNA and DNA

34
Q

DOC for Histoplasma capsulatum a most common systemic fungal infection

A

Amphotericin B

35
Q

Most toxic of all antifungals

A

Amphotericin B

36
Q

Amphotericin B is administered/given

A

IV

37
Q

DOC for Candidiasis: Oral, esophageal, corneal, conjunctival.

A

Nystatin

38
Q

Swish and swallow, not used for systemic fungal infection

A

Nystatin

39
Q

doc for Systemic Candidiasis

A

Amphotericin B or with Azoles

40
Q

Most toxic antifungal

A

Amphotericin B.

41
Q

Most toxic among Azoles

A

Ketoconazole (Nizoral)

42
Q

Aspergillus microorganism has a ___ that leads to cancer

A

Aflatoxin

43
Q

DOC for Aspergillus, backup for Candidiasis

A

Itraconazole

44
Q

drug that Flows/Crosses to Blood brain barrier, DOC for cryptococcal meningitis

A

Fluconazole

45
Q

DOC for Tinea, Dermatophytosis (Skin Fungal infection)

A

Terbinafine

46
Q

Important for inflammatory response

A

Histamine

47
Q

Major source of Histamine

A

Mast Cell

48
Q

DOC for Herpes

A

Acyclovir
IV - Nephrotoxicity
Oral - GI

49
Q

Amantadine an antiviral drug that can be used in neurological disorder -

A

Parkinson’s Disease

50
Q

Which antiviral drug is effective for Parkinson’s disease

A

Amantadine

51
Q

HAART

A

Highly active anti retroviral therapy (HIV Positive)

52
Q

MO that causes subgingival caries

A

Bacteriodes Melaninogenicus

53
Q

Anti-TB drug

A

R. I. P - most important
E. S.

54
Q
A

DMD (24 decks)

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