amphetamine Flashcards
ephedrine
orgin
botanical origin (ma huang)
sympathomimetic: bronchial dilation can treat asthma
increases blood pressure
synthesized amphetamine
street name: speed
administration: oral
can be used to treat ADHD
methylated amphetamine
crystal, meth, ice
passes BBB quicker
amphetamine mechanism of actions
leaky vesicles, reuptake inhibitor
- norepinephrine, dopamine, serotonin (small)
inhibit monoamine oxidase (MAO)
– increase dopamine similar to antidepressant
amphetamine dependance
psychological cravings- depression, anxiety, insomnia
met is associated with allostatic/ degenerative changes
amphetamine tolerance
tachyphylaxis possible - few hours
residential study meth
reported positive effects on first day of meth then flulike sim atoms and disrupted sleep and decreased food intake
amphetamine widhrawal
lethargy, depressed mood - may be serotonin
amphetamine psychosis (withdrawal)
paranoia, panic
compulsive, repetitive behaviours
delusions, hallucinations
dopamine release similar to schizophrenia
tweaking- irritability, paranoia, violent behaviour
formication
perceiving bugs crawling under the skin