Abnormal cellular component in pap

Question 1

Budding yeast seen among diabetics, taking oral contraceptives, immunocompromised patients, prolonged steroid therapy; also called moniliasis

Answer 1

Candida albicans

Question 2

Pear-shaped organism, STD, granular cytoplasm, eccentric dark nucleus

Answer 2

Trichomonas vaginalis

Question 3

Tiny pleomorphic coccobacilli that cling to the cytoplasm of epithelial cells

Answer 3

Gardnerella vaginalis

Question 4

Squamous epithelial cell that shows cytopathic effects of HPV; nucleus appears as a wrinkled prune surrounded by a perinuclear halo

Answer 4

Koilocytes

Question 5

Presence of koilocytes diagnosed as low-grade squamous intraepithelial lesion

Answer 5

Low-grade squamous intraepithelial lesion

Question 6

Cytopathic effect characterized by macrosomia, multinucleation, nuclear molding, and ground-glass chromatin pattern

Answer 6

HSVII

Question 7

Epithelias associated with cancerous lesions

Answer 7

Carcinomas

Question 8

Cervical mucus in pregnancy; on drying exhibits a fern or palm tree leaf pattern due to increased estrogen effect

Answer 8

Ferning arborization

Question 9

Formation of salt crystals (high NaCl concentration) under the influence of estrogen

Answer 9

Basis of ferning pattern

Question 10

High persistent estrogen effect in the absence of progesterone; basis for early pregnancy diagnosis

Answer 10

Positive ferning

Question 11

Marked progesterone effect, at least 50% of intermediate cells in clusters, presence of 3-7 pregnancy cells, less than 30% superficial cells, presence of Doderlein bacilli

Answer 11

Criteria for cytologic diagnosis of normal pregnancy

Question 12

Percentage of cells that stain pink-orange to red with Pap’s stain and red with Shorr method

Answer 12

Acidophilic index (A.I)

Question 13

Percentage of cells having shrunken dark, small (<6 µm) nuclei

Answer 13

Pyknotic index (P.I) / Karyo-pyknotic index

Question 14

Percentage proportion of cells from the three layers of the vaginal epithelium

Answer 14

Maturation Index (M.I)

Question 15

Two systems: Class system (obsolete since December 1988) and Bethesda system (developed at NCI)

Answer 15

Manner of reporting Pap smears

Question 16

Obsolete system based on the presence of malignant cells; no classes for non-cancerous entities; not reproducible

Answer 16

Class system

Question 17

Negative for malignant cells

Answer 17

Class I

Question 18

Atypical cells present but negative for malignancy

Answer 18

Class II

Question 19

Suspicious for malignant cells

Answer 19

Class III

Question 20

Strongly suggestive for malignant cells

Answer 20

Class IV

Question 21

Conclusive for malignant cells

Answer 21

Class V

Question 22

Developed at the National Cancer Institute in December 1988; includes specimen adequacy, general categorization, and descriptive diagnosis

Answer 22

Bethesda system

Question 23

Categories: satisfactory, limited, unsatisfactory

Answer 23

Specimen adequacy (Bethesda system)

Question 24

Negative for intraepithelial lesion or malignancy; epithelial cell abnormality; benign cellular changes

Answer 24

General categorization (Bethesda system)

Question 25

Includes infectious/radiation effects, atypical squamous cells of unknown significance, low- and high-grade squamous intraepithelial lesions, squamous cell carcinoma, glandular cell abnormality, atypical glandular cells, adenocarcinoma, others

Answer 25

Descriptive diagnosis (Bethesda system)