83 - Fox-Fordyce Disease Flashcards
Chronic, itchy, papular eruption involving apocrine gland-rich areas of the body
Fox-Fordyce disease
Fox-Fordyce disease is otherwise known as
Apocrine miliaria
Fox-Fordyce disease disproportionately affects
Females between the ages of 13 and 35 years
Fox-Fordyce disease most commonly affects the
Axillae
(Increased/Dimished) sweat production is frequently observed in affected areas
Diminished
(Y/N): There is evidence that Fox-Fordyce disease progresses to hidradenitis suppurativa
No - no evidence
The tendency of Fox-Fordyce disease to present at _____ and remit after _____ suggests a hormonal component to the disease
Puberty
Menopause
Improvements also have been reported during _____ and with use of _____
Pregnancy
Oral contraceptives
Y/N: Several case reports have been described Fox-Fordyce-like eruptions developing after laser hair removal
Yes
Most consistent histopathologic finding in Fox-Fordyce lesions
Hyperkeratosis of the infundibular epithelium and dilation of the follicular infundibulum
The existence of the pathognomonic _____ is constroversial, as these vesicles are rarely demonstrated in histologic specimens
Sweat retention vesicles
There is evidence that _____ sectioning produces a higher yield of hair follicle units and more readily demonstrates the histopathologic features of Fox-Fordyce disease
Transverse
Systemic therapies to alleviate itch in Fox-Fordyce disease
First-generation oral antihistamines
Low dose doxepin (<10 mg), up to 3 times a day
Y/N: There is evidence to suggest that shaving or deodorant use worsen symptoms.
No - no evidence
Y/N: Thick creams and lotions, which can exacerbate follicular obstruction, should be avoided
Yes
